reaction to methotrexate.

I have been on Prednisone for about 6 weeks (started at 15 mg/day and slowly reducing ; now at 9) and feeling better and better. My rheumatologist started me on Methotrexate last week ( 15 mg once a week), while slowly reducing the Prednisone. I've had a bad reaction: aches in joiints that never hurt before and a feeling of increased weakness. The worst time of day for me has been from about midnight to midmorning, when the symptoms faded. I have been feeling a bit better each day and am almost bact to where I was before I started Methotrexate. I'm afraid to take a second dose this week.
Has anyone had a similar reaction? Any suggestions?

I'm really new to this, just dx in jan, but i agree with yalinda it's prob the decrease in the pred rather than a reaction to the mtx. when my docs took me from 20 to 10 of pred my pain shot up so high i had to go back to the hospital in what they called a "pain crisis" the team of docs agreed that they took me down on the pred way too fast. now they won't do a decrease of more that 2.5 over a 2 week period, and even then we watch the pain closely. hope that helps. I know that just other's experiences is what i am looking for and it does seem to help.

This could definitely have been rebound pain from pred withdrawel.
Tell your doc what happened.
Could be this round of MTX will be easier.
Also, maybe find out what you can do or what can be RX'd for pain while getting off of the pred.

Best wishes.