Hi.
I don't know that enbrel or humira would be a step up to remicade. Many others might consider remicade a step up from enbrel. My rheumy considers all of them rather equal, and very individual. what works for one person may not work for another, tra-la-la.
I was on enbrel injections for close to a year, and I can tell you I would much rather give myself an injection (it's not that bad) than have to take a whole day getting an infusion. Plus, I believe with enbrel you have the sure click option, which makes the injection that much easier. I've never used sure click, but I believe others on this board have.
The advantage of remicade, though, is that you only have it done every 6-8 weeks (depending on the patient). Keep in mind that for a lot of people, myself included, it took a long time for the enbrel to kick in (don't know about remicade). It me almost 7 months before I felt any significant effects from the enbrel; however, it can take as little time as 2 weeks.
Best of luck with the remicade.
El