I took it for probably 5-6 years with great results. Then my liver got kinda messed up. Since it requires pretty high dosages (I think I was taking about
650mgs. daily). Things got screwey, not because of of the Valporic Acid (Depakote), but because I had a surgery and then got hit by a truck so I ended up on pain meds. That's when the liver began to protest. I would recommend it to anybody. Just not for me right now. Maybe after I get weaned off some of these other meds.