Depressed spouse, need suggestions

can someone please help me? I have been with me wife for ten years now, and about five years ago she was diagnosed with bipolar disorder. it has been a roller coaste ride. I love her very much and plan to spend the rest of my life with her. she is medicated but has recently slipped into one of her worst depressions. she almost left me because she feels like she needs to be alone. she fells guilty for putting others through her pain
. any suggestions to help me or to help bring her back to the light would be awesome thanx