Is Gilbert syndrome a new risk factor for breast cancer?

http://www.ncbi.nlm.nih.gov/pubmed/21636218 said...
Abstract
Patients with Gilbert syndrome have an impaired function of the enzyme UGT1A1, responsible for the degradation of 4-OH-estrogens. These elements are produced by the degradation of estrogens and are well-known carcinogens. In theory, patients with Gilbert syndrome accumulate 4-OH-estrogens and, therefore, might have a higher risk for breast cancer, especially when exposed to higher levels of estrogens. If this theory is true, a new risk group for breast cancer would be described, producing new insights in breast carcinogenesis.

[url]http://www.ncbi.nlm.nih.gov/pubmed/21636218[url]