I've been using Avinza (ER morphine) for about
3 months. You take it once daily. It does help but I am going to speak with my PM on my next visit cause I think that there are days when I could get by without the meds but am scared of withdrawl symptoms if I don't take it. I also have oxycodone for breakthrough but don't need unless I overdo it or a weather front comes through that always makes me very sore. The constipation was bad at first with this med but got better after a few weeks and I was back to normal. I used Miralax until my body adjusted.