Hey again Chelsea...I didn't want my post to frighten you, but the Synvisc One shots are excruciating, even with the numbing med. It's because the ortho is injecting the HA deep into the "joint". The substance provides a "cushioning" where mine has deteriorated, causing bone on bone grinding pain. You will be asked if you have any known allergies to poultry. Having said that, the injection pain subsides and I feel a difference within a couple of weeks. Synvisc One has been a miracle for me, personally. I will continue to have them as long as they allow me to walk.
If the source of your knee pain is yet to be determined, I can't see where Synvisc would be right for you. As others have said, the cortisone injection is a simple fairly painless procedure. It will be very helpful for inflammation and perhaps relief short term.
I am not aware of ANY injection in the knee or otherwise that provides "permanent relief". I would question any doctor who made that statement.
I hope you find some answers, and some relief.
~~Dixie