When I used to get the shots on the clinical trial, there was once or twice where it seemed like I had a little difficulty breathing, but it went away. I don't know if it was a reaction or just the fact that I had to walk several blocks to the hospital before and after. I've been on it for about
a year again (was on it for a year during the trial and then tried Humira for a year) and have not had this problem again. Only side effects I ever get is the occasional white whelt around the injection site. Ask your dr. if you have the reaction again. I asked the clinical trial people and they said no one in the trial had had the reaction, so they thought mine was caused by something else, but you never know...everyone reacts differently.