Azathioprine vs 6-MP

✚ New Topic ✚ Reply

Cronico

Regular Member

Joined : May 2010

Posts : 64

Posted 7/12/2012 5:10 PM (GMT 0)

Which one is the best in terms of side effects and efficacy?

NiceCupOfTea

Elite Member

Joined : Jan 2010

Posts : 11145

Posted 7/12/2012 11:48 PM (GMT 0)

Basically equal in efficacy, but 6MP would appear to be the slightly better tolerated drug.

Scroll down a little ways:

http://www.gastrotraining.com/category/pharmacology/azathioprine-6mp

ski bum

Regular Member

Joined : Jan 2007

Posts : 451

Posted 7/13/2012 2:10 AM (GMT 0)

My GI told me that Azathioprine breaks down into 6MP and something else and the something else may be beneficial. So he prefers to prescribe Azathioprine over 6MP.

Cronico

Regular Member

Joined : May 2010

Posts : 64

Posted 7/13/2012 3:02 AM (GMT 0)

thank you very, very much! I am really scared... but, unfortunately, there is no other way, except TNF inhibitors... Entocort has put me in remission, but is beginning to cause bone loss. i hate this disease!

NiceCupOfTea

Elite Member

Joined : Jan 2010

Posts : 11145

Posted 7/13/2012 3:26 AM (GMT 0)

Hopefully Aza or 6MP will work - you've got an advantage by already being in remission. Takes 2-3 months before they start working, however, so you should probably stay on the Entocort until then. Good luck.

(And yeah, I'm not too fond of this disease... :-/)

✚ New Topic ✚ Reply