I hae been on humira for 2+ years and have minor injection site reactions for 1-3 days. I also get hives. Sometimes these are following an injection, other times it seems random. I had never had hives prior to starting humira.
However, this has allowed me to have 2 beautiful children and almost remission for the past 2 years. I was on remicade until I developed anti-bodies and had to switch.