I went to UNC-chapel hill GI research clinic on Friday. My GI wanted input on next steps of my treatment. Given that I had an awful scope last month and that I have tried remicade, metho, cimzia and had a bowel resection,. he wanted to review options. I also got pnuemonia while on remicade. I did stop all crohn's meds fro the past 12 months to allow my system to fully recover and I have felt the best I have felt in 4 years! however, the CD has silently done is damage to my system. I will say that the past 2 months i have exhibited more tradition CD symptoms so we all knew I had to go back on meds. I have also tried 6MP which made me throw up much like methotrexate.
So the answer is to try humira on its own. do another scope in 3 to 4 months. Be prepared to go to weekly injections and scope again in another 3 to 4 months. He thinks that the biologics may not fully put me in remission as even while on remicade (full dosage) with metho I still had smome ulcers. But that we need to get back to that level to prolong the need for surgery.
My wife and I are excited that we have a plan and we will be looking at progress via a scope on quicker cycles so we can make adjustments. This guys says that for patients like us the research and thought is changing to have the scope more frequently than in the past.