Howdy all. I just had my beginning dose of Humira today. I've done other biologics in the past (Remicade and a research study drug) and they were done by iv. These shots are so much different. I ended up doing three in my legs because the one in my abdomen hurt so much worse. My question is what can I do about the ache in my legs? They are just so sore. It hurts to walk, heck it hurts to lie around. I can deal with the tired/drowsy feeling as that is pretty much my everyday at this point lol. Thanks in advance you guys :)