Anxiety

It's certainly a possibility. Some people get more anxiety while they're on it; others, while they're tapering off of it.

Suffer from bad anxiety generally, but it was not made worse by Pred. In fact being on Pred was the only time I ever felt emotionally good, to be honest. Had more self-confidence and energy and just generally felt far happier than I ever have done since surgery.

I'd have stayed on it for the rest of my life if it didn't wreck every system in your body.

I remember having anxiety once when I was on prednisone. My heart would start beating fast for no reason and I once went into a full blown panic attack! It was horrible! My dr gave me a prescription for Ativan that I now carry with me all the time, "Just in-case". But I haven't felt that way in a long time. I try to do deep breathing techniques, workout, do yoga, or take an epsom salt bath to help me relax. It helps, but it certainly took time for me to get over. That prednisone is so good at helping, but I often wonder if the side effects are worth it!