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Posted 6/16/2008 10:18 PM (GMT 0)

hi guys,

it's been a long time since the last time I visited this website....I am o.k. I have bad days and good one...since my dx I haven"t been in remission....I am in a research study for the drug named Ababtacept(orencia) I've been on it since dec 07 .

I had my crp level check in march and it was 16 and last week I had another one and it is 27.3...I've done these 2 test threw my GP cuz it's a double blinded research and my gastro is not supposed to know.neither should I but everyone was saying it was food and stress related and I wanted to know for myself.

should I do something about it? I am not in alot of pain it is very barable since I don't eat meat,milk products and gluten.

Posted 6/16/2008 10:40 PM (GMT 0)
sorry if I sound stupid but what is crp levels?
Posted 6/16/2008 10:47 PM (GMT 0)
CRP is c-reactive protien-it is a measure on inflamation that is more responsive than sed rates. It is not selective so any cause of inflamation including infection will raise CRP.

Only you can decide wheather to do something about your condition. Do you feel the trial is helping you, if you decide to treat yourself with something other than study meds do you have ot withdraw from the trial...I guess I would concider everything before making that kind of decision.
Sj
Posted 6/16/2008 11:17 PM (GMT 0)
Hi So glad you dropped in, have been thinking about you .I haven't a clue what you should be doing. Are you feeling worse since March?What did your Dr. say about it? So are you finding this med right for you. I ended up getting a resection in Jan. not long before I was supposed to go to Halifax. On no meds now but getting lots of body aches. Sure hope someone else who has more insight on your rates can help. Perhaps you could ask them to give you a blood test bacause your not feeling the greatest. lol gail
Posted 6/16/2008 11:48 PM (GMT 0)
I dont see the units on your numbers,,,is it in milligrams per liter?..The normal level of C Reactive Protein in your blood should be up to 4.9mg/L (4.9 milligrams per liter). This is level of C Reactive Protein in the average healthy person.
Posted 6/17/2008 3:45 AM (GMT 0)
My CRP has been off the charts for three yrs. Highest 164. When I first started getting sick it was 22. This test alone is a measure of the presecnce of some kind of inflamation. These numbers are greatly affected by many different things. Doctors will now state that they can't make a diagnosis just based on the CRP level since it can't pinpoint where exactly the problem is and with an autoimmune disease there could be several locations and reasons for the inflamation. The test can be used in conjunction other lab results. With my Crohn's, doctors knew I had some kind of inflammatory condition but were not sure where or what it was. Since I had SVT(arrythmia)I had cardiac ablation. The numbers did not drop. Several trials of methotrexate, remicade, humira and so on still didn't bring the number down. Years ago doctors relied on this as a marker for potential heart problems or stroke. Now they understand that they may need more. Standing alone it may not accurately diagnose a person but it will indicate the level of inflamation prompting further investigation. Steriods will elevate a persons CRP level.
Posted 6/17/2008 3:42 PM (GMT 0)
thanks for the info.
gachon- happy to hear from you.I hope you remain in remission for a long time....

I am still not sure what to do.I know i am allowed to take pred with the study .I haven't talked to my gastro yet. I guess I will just wait cuz I am not really in pain right now. as for the study I think it's working...but I know there's a huge difference when I don't smoke so I quit .

thanks
Posted 6/17/2008 3:51 PM (GMT 0)
I thought birth control pills also elevated the CRP? It seems like, while mine is always high, it's way high when I am taking the pill. Anyone else know about that?
Posted 6/17/2008 11:20 PM (GMT 0)
Hey so glad you quit I tried and started again but good to know it can be done .I did feel better too not as tired. How long before you see your GI? lol gail
Posted 6/17/2008 11:48 PM (GMT 0)
thanks gachon...I kinda see him every month for a check up before I take my IV meds but sometimes there's another GI who does the check up I think I will see him in july but not sure.

I thought that have a high CRP level meant that you had active inflammation and that it was dangerous to have a high crp because of heart attacks?
oh well I'll ask at my next appt ....
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