Posted 5/31/2010 2:18 PM (GMT 0)
this is from the mayo clinic site:
Azathioprine (Imuran) and mercaptopurine (Purinethol). These are the most widely used immunosuppressants for treatment of inflammatory bowel disease. Although it can take two to four months for these medications to begin to work, they help reduce signs and symptoms of IBD in general and can heal fistulas from Crohn's disease in particular. If you're taking either of these medications, you'll need to follow up closely with your doctor and have your blood checked regularly to look for side effects.
Methotrexate (Rheumatrex). This drug, which is used to treat cancer, psoriasis and rheumatoid arthritis, is sometimes used for people with Crohn's disease who don't respond well to other medications. It starts working in about eight weeks or more. Short-term side effects include nausea, fatigue and diarrhea, and rarely, it can cause potentially life-threatening pneumonia. Long-term use can lead to scarring of the liver and sometimes to cancer. Avoid becoming pregnant while taking methotrexate. If you're taking this medication, follow up closely with your doctor and have your blood checked regularly to look for side effects.