Posted 12/13/2014 10:52 PM (GMT 0)
I have had Crohn's Colitis for 25 years. I had an allergic reaction to Remicade after the second round. Did Humira for 6 months and gained 80 pounds and eventually went into remission. That was 6 ears ago. I have been having difficulty controlling the current flare for about a year (now on the third round of the dreaded pred). My doctor is suggesting we try another round of biologics or look at surgery. Since I have already done the Humira (and Remicade), he is now considering either Cimzia or Entyvio. I know that all three drugs are biologics and that Cimzia and Humira are both TMF-blocking agents but I am still unclear as to what the difference is between the 3. If I did not respond to the Humira, am I more likely to respond to either of the other 2. How do the side effects compare? What is the advantage of one over the other?