Hospitalized--6mp and remicade or entyvio? Upset

If anyone was following my last post about severe stress and avoiding a flare well, it didn't work out well. I thought I was doing pretty well and followed the tips as well as those of my Doctor. None of my normal "I'm heading for a disaster" symptoms but a few pains that warranted looking into that had only been for one day. Totally thought I was over reacting, I think my doctor did too because he thought my ct scan looked decent and that it was mainly from the stress. Unfortunately after feeling better for a few days, I didn't make it to the week mark when we were going to check in to see if I felt like I needed a short course of prednisone. I woke up to terrible feelings like digesting glass shards and knives. (Meanwhile my mother is still in the CTicu for over 40 days, from open heart surgery complications to her lungs after having endocarditis) i barely could get out of the chair I slept in at the hospital at her bedside but made it out to run To take care of our pets. Well the whole day was spent with me throwing up the entire way back while trying to drive on the highway. But I had to make it back to the same hospital because I didn't need us to be in different places. Went to the ER. Apparently partially obstructed and I was admitted. They couldn't figure out why my doctor didn't take it more seriously based on the ct record. Now I've been here 6 days and still no sign that I will be able to have solids anytime soon since the last try did not workout well and a third cT showed things were still bad despite high doses of iv steriods. I have new GI doctors here since I'm in a totally different area. I feel pretty confident in them but yesterday the doctor told me if I didn't take serious meds now I would be heading for surgery in the near future. We now wonder if the Humira I was on ever really put it in remission though it had appeared to be helping.

They basically aren't letting me out with out starting a combo either 6mp and entyvio or remicade though leaning to remicade. Any thoughts on these combos and experiences with them? I completely wanted to avoid combos because of the added risks but now here I am. They said only a year for the 6mp then just the biologic. Really overwhelmed with having to deal with this as well as keep track of my mom's health. ( Hospital has been fantastic though and I now know pretty much every doctor, nurse and staff member and seen them work some miracles over the last two months so I've managed to keep a positive attitude which has made this a bit easier)

You've been going through such a terrible ordeal. Just the worries of your Mom I'm sure making it tough to think of your own health and getting better.

Remicade is still the state of the art drug for Crohn's. It seems to still show the best results of all the biologics. Combination therapy has proven to make a significant difference in the long term success of treatment. It really helps to reduce the liklihood of antibodies.

I really hope you and your Mom are feeling better soon. Please keep us posted.

If you are not responding to the steroids then the obstruction might be due to scar tissue rather than inflammation. If scar tissue is the issue, then no medication is going to help. That's what happened to me and I ended out needing surgery. I agree with the others that if this is an obstruction due to inflammation, then the Remicade makes sense.
I'm so sorry about your mom and all the stress you are going through!

Thanks everyone! The responses help so much, as soon as I'm feeling a bit better I'll write more but I started 6mp two days ago now and today will be my first remicade infusion. I never wanted to be on two at once but here we are. They have been trying to rule out a stricture but the doctors are pretty sure it's just a severe partial obstruction that if let go any further would be and would need surgery but right now if the meds kick in it should be okay though I have a surgeon following it. Usually prednisone works fast for me but the iv high doses have taken over a week now to get to the point where full fluids are allowed and I still feel a bit ill from them. It's just crazy how the pain and the severity of these situations can come with such little warning sometimes. It still shocks me. My mother continues to improve, still a long journey but her amazing progress and the support of the amazing hospital staff has helped me relax a bit and focus on my own health.

Personally, I think Remicade is still the best drug available for Crohn's (never tried Entyvio but I am not impressed by the anecdotal responses I have read). Depending on how significant the inflammation is, it can take a while for the steroids to kick in, so have faith!

I was on Humira for 4 years, it stopped working in year 3.

Then I was put on Entyvio and everyone kept saying that you must wait until at least 5 infusions until you see any effects. Welll I went to 7 infusions, at $4900 each and the bill to the insurance company was over $32000. No results at all. In the office where I go with 4 GI doctors there were 15 Entyvio patients, 10 it worked somewhat and 5 did not work at all (like me).

Now I am on Imuran and Remicade, 3 infusions at $6800 each, have not seen any results yet. I feel that this is the way to go even though it takes 2.5 hours per infusion.

I responded very well to the Stelara clinical trials and I am anxiously awaiting for it to be released to Crohns patients (right now it is only for psoriasis which is given by injections of 80mg each. Talked with the head of reseach for the Uniti-2 study of stelara of 690 patients and they had very good results at 400mg infusions, 5 times what the psoriasis people get.

Thanks Fernando and Christine1946! Yeah I have no idea how I will tell what is working or not working since I just started this cocktail all together other than if things go wrong with blood work it will point to negative effects but I could be on one that is working and one doing nothing and won't know it and probably won't even know that much until I'm off of the prednisone. I hope you are able to get the stelara, Fernando because that sounds promising. Your info definitely helps Christine, and answers some of the questions I asked in one of your other posts. I didn't do the entyvio because it wasn't available at the hospital which I am totally fine with. I got the feeling the doctors wanted to use it cause it was the latest thing but I'm happy to start with remicade instead. 6mp not as happy about but giving it a go. The steriods and maybe the remicade (doubt 6mp would have done anything yet) definitely showed improvement on my last ct scan so let's hope it continues. Though now I feel generally crumby like I have a fever or cold and can't have a proper bowel movement which was actually totally normal before I ended up in the hospital. So fix one thing start something else. I have a follow up tomorrow to address it all.