Remicade dosage doesn't seem right.

I wouldn't lose the muscle if you've worked hard to gain it and want to keep it. Talk to your doctor about the reason for your weight gain and wanting to lower the dose - it may well be that you are on a higher dose than you need to be. What dose are you on now, do you know?

They actually usually round the dosage, though, to the nearest 100. When you started, you weighted 165 lbs = 74.8 kg. Multiply that by 5 mg, and you get a dose of 374 mg (which they would probably round to 400 mg). Now you weigh 211 lbs = 95.7 kg, giving you a dose of 478.5 mg, which would probably round to 500 mg. But that jump from 400 mg to 500 mg would have happened only one time, and at 90 kg, or 198 lbs. I don't think that it's the dose making you feel crummy.

I agree with @scifigal and @NCOT. How long have you been on it? Let your doctor know whats going on and ask about checking your Remicade level. everyone is unique to some extent in what level works best for them though generally i believe between 5 and 7 is ideal. I do better with it higher around 11 but I do have crumby periods like you describe, however they were worse when my doctor lowered the Remicade dosage to see if that would get rid of the body aches and general ill feelings. I ended up going back to the 5 mg/kg dose and with in 3 weeks of the lowering the dose.

Yeah... I try not to think about it. In general it gives us some form of life back. 11 years, that's really fantastic though! Maybe it's not enough if at some point you went from 10 back to 5? I don't know, it always gets a bit confusing at least in my experience trying to figure out what is causing what .