Entivyvio vs Humera

I've had Crohn's for over 30 years & have been on Asacol & Imuran. My GI said they're not working because I now have a narrowing in my descending colon, & wanted me to start biologics. I started Remicade in October, & from the very beginning, I had problems...palpitations with panic attacks, bad heartburn, throat pain & now Psorasis that is getting worse even with steroid creams. After my last treatment in December, I decided to discontinue Remicade, so my doctor suggested Entivyvio since it goes right to the gut. My dermatologist however suggests Humera to help with Psorasis & the joint pain I've also been experiencing. Since Entivyvio is not systemic, it shouldn't cause other problems. I don't know what to do.

When I was on Remicade after being on it about 3 years, all of the sudden psoriasis reared its head. To this day we have no idea why. I was then put on Humira, my dr warned me that more than likely the same thing would happen & it did. I had 4 different kinds of psoriasis hitting at one time. I ended up with cellulitis in both legs along with staph infections. I finally went off Humira, I got tired of being in & out of the hospital because of the staph. Not saying this will happen to you, but Humira & Remicade are similar.

I would do a little more research & then make a decision.