Wenmarie, my daughter was put on Topomax a few weeks ago, is now tappered off. The highest dose she went to was the starting dose of 25mg. Her pdoc put her on it for irritability and said it would also help with the weight loss that she had encountered from the side of effect of zoloft. She also said that if my daugher still felt some depression after being on this she could maybe try a small dose of zoloft again with it.
She said that they are finding it to work with persons with Bi Polar. I had also read about it on a web site that it is used for people wheo have weight gain from their other anti-depressents. She had said it was also a mood stabilizer.
It made my daughter very tired, unable to consentrate or remember what she talked about the previous day. She was also becoming withdrawn again, very flat line, meaning just kinda their. Not having any ambition to do anything.
She has been off now for two days, we will have to see if her irritablity is still a problem. This wasn't really a problem until she was on Wellbutrin XL. We have tried a few different routes since coming off zoloft. I do beleive the side effects of the zoloft were mistaken for some other problems, such as irritability, mood swings, and etc.
Good luck to you, just know that your not alone out their! Be sure and let your dr. know what your feeling like joanne noted.