Anyone takes 450 mg Bupropion?

Med nurse increased my dosage from 300mg to 450mg.

While researching, I learned that there is some negative effects associated with the higher dosage.

Curious to see if anyone took it at that dosage and how they responded to it. Yes, I know everyone responds differently, but I'm still curious.

450 mg is a very high dose I rarely see it usually sleep disturbance, agitation can occur at that dose.