I can understand what you mean by nothing feeling real. I get that too. Sometimes it only lasts for hours but sometimes it lasts for days. It feels like a veil has been lifted from the world and I'm seeing everything clearly for the first time--but it really freaks me out. The only way I can make it go away is to go to sleep. My anti-anxiety meds don't work when I feel Like that.
I know what it feels like to feel hopeless. Like no matter how hard you try nothing is ever going to change. But I've been taking my medicine and going to therapy for a few years now and it's finally starting to work. They diagonosed me bipolar after the anti-depressants made me become manic, so I had to start all over on new medicine. And it took a little over a year for the meds to finally start working, but now that they've kicked in, they have really helped.
I don't know how long you have been going to therapy or taking medicine, but give it time. If you stick to it, it really does start to help. Although you may feel like there is no other way, don't give up. It can get better and you don't have to feel like this for the rest of your life.