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Desvenlafaxine (generic Pristiq) and Horrible Dry Mouth

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Posted 4/16/2017 3:26 PM (GMT 0)
Hello all,

I started taking the generic Pristiq (desvenlafaxine) a couple of days ago because my insurance no longer covered the brand name. I've had horrible dry mouth since (not an issue with brand). Last night it was really bad - it felt like I had no saliva whatsoever, like my tongue was pasted to my mouth (sorry for being gross!)

I'm going to call my doctor tomorrow. Meanwhile I don't want to take it again tonight. (I have a bad sore throat now, though the dry mouth is a lot better). I'm thinking about continuing to take the brand name until I can titrate off with doc's supervision.

Has anybody ever had terrible dry mouth on desvenlafaxine? Any suggestions?
Posted 4/16/2017 6:18 PM (GMT 0)
I get a dry mouth but it subsided. You probably need to drink more water. That would help you to feel better too. Be careful going off of it if you have been taking Pristiq awhile. After a day or two, withdrawal symptoms happen and that is no fun.

Did you drink any water when your mouth was dry? If not that is probably where the sore throat came in, unless you picked up a bug of some sort.

I hope you feel better. Your doc may have some samples of the real pristiq for you. I had no trouble switching, Thank God, it seems the same to me. I looked at the price of the generic and it still was super expensive. I take 150 mg a day.

Welcome to the forum Caliope.

Hugs, Karen...
Posted 4/16/2017 8:02 PM (GMT 0)
I am on Celexa and still get bad dry mouth it is a side effect of antidepressants. I always keep water next to my bed for this reason. I am okay during the day but at night I get dry mouth and Karen is right it does easy off. Once you are use to it.

If the medication helps try chewing something healthy before bed so your glands will work more at night. I have also done this as well. I can't chew gum, allergic to it, but that can help. My aunt holds hard candy in her mouth even right before bed too.
Posted 4/16/2017 9:45 PM (GMT 0)
Thanks for tips/ suggestions!
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