I never had any bad side effects from Lyrica. It just crapped out after a while so he added cymbalta. You have to play around with your medicine. If you take it once a day, pay attention to how if makes you feel in the morning, night, etc. I have to take my cymbalta at 2:45 in the afternoon. If I take it too close to bed time, it keeps me up at night. If I take it in the morning, I am tired WAY before bed time. So, yah, try taking it different times of the day if you can. And give it a good month or 2 before you give up in it. I know it sounds like a long time but you'd regret if if it would end up workin for you. Good luck