Posted 11/1/2013 11:14 AM (GMT 0)
With high creatine you should have your kidneys thoroughly checked out.
I had a 1:160 ANA speckled pattern years ago and then it gradually came down to 1:40 over the next year. Like you, Rheumy tested for all common autoimmune disorders and was negative.
I would definitely get that high Creatine checked out (are you on any meds that could be driving that up?).
If second Rheumy opinion is negative, consider diet.
Do you have any gastro problems?
Have you tried a strict gluten free diet?
(need to do this at least 3-6 months to give time for healing before you know if it's helped).
Also please see my post on histamine and mast cell release.
A low histamine diet has been extremely helpful more than anything else I've tried.
Finding and treating any hidden bacterial infections might bring the ANA levels down.
These are things that have given me improvement in the long haul.