Oddly, bras don't bother me...and I wear an underwire (mostly cotton-ish.) Almost everything else does, though! I'm ultra-picky about
the right material, loose fit, you name it - but I've lucked out there. Of course, it does take forever to find one that fits right (34C) and that I can bring myself to spring for....because I hate paying much for anything.
That doesn't mean it doesn't feel good to take it off at night, but I never think of it until then. Now changing from shoes to slippers - that's my moment of, "Aaaah!"
Debbie