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C-reactive protein level.

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Posted 6/29/2014 11:07 PM (GMT 0)
I had blood work done a few months ago. All of the preliminary stuff came back normal, WBC, RBC, Lyme, rheumatic all normal but my C-reactive protein level is 10.6 which is high. My rheumatologist showed no concern, didn't even call me. My psychiatrist said that I have some inflammation somewhere and that he'll add that info to my chart. I'm growing more concerned about the high level because iv been reading that it affects the heart. I don't know what to do. Does any one else have a high CRP level?
Posted 6/30/2014 6:39 AM (GMT 0)
I do but it's from my lupus.
Posted 6/30/2014 4:13 PM (GMT 0)
I actually don't know what mine is really. It had a note saying that carboxypenicillins can cause a falsely decreased CRP level due to analytical interference and it hasn't been checked since then. I was on Keflex at the time because of a UTI I didn't even know I had.
Posted 7/3/2014 10:24 AM (GMT 0)
I haven't had it but my husband did. It was due to his statin meds . Not sure if u r on any but it may be worth looking into.

My husbands neurologist had him do some exercise ( he went to the gym) then immediately get tested again.

Everything turned out fine for him. I wish u the best.
Posted 7/3/2014 3:38 PM (GMT 0)
I asked for a c-reactive protein test one time and it was high and the drs. office called me to see if I had been sick or injured. I hadn't and haven't heard anything about it since.
Posted 7/4/2014 6:28 AM (GMT 0)
I hav seen both elevated ESR (Erythrocyte Sedimentation Rate) and C-reactive protein reported on forums by fibro patients without a secondary condition that would explain the presence of these inflammatory markers. I am just on a cell phone right now but if u look for a study with these keywords,(edit: the link is in my next reply) you will find one of the studies that used a test they called "high-sensitivity c-reactive protein" (hs-CRP) (& looked for ESR andsome cytokines--- a couple of inflammatory cytokines) Search: study abstract fibromyalgia high-sensitivity c-reactive protein Xiao Russell. To find other studies I would do a search for study abstract fibromyalgia C-Reactive Protein. I usually use Google. More info out there, for example fibro people with either higher CRP or ESR seem to do better with low dose naltrexone (LDN) than those without. I can't remember which one. And I don't know if they checked for both.

Post edit. Studies linked and summarized

This is a thread about fibro studies looking for markers of inflammation. Over 30 up to 2015 found some evidence. I added a study from March 2017 to demonstrate that the findings continue. Included in the linked thread are some studies with CRP and SED/ESR findings.
/www.healingwell.com/community/default.aspx?f=24&m=2756942&g=2756942#m2756942

Post Edited (Rockon) : 12/26/2017 10:18:05 AM (GMT-7)

Posted 7/7/2014 12:03 PM (GMT 0)
I decided just now to copy/paste the keywords I gave you (quite a delayed after-thought) and that study did come up on my google search:


/www.ncbi.nlm.nih.gov/m/pubmed/23124693/

As I reread the study, I noticed they offered a link to another study from a Xiao team, about a genetic polymorphism they found connecting higher CRP accompanied by higher body mass index (BMI) in fibro patients to a genetic snp (pronounce it "snip". Stands for single nucleotide polymorphism) at the gene labeled BDNF (Brain-Derived Neurotropic Factor).


/www.ncbi.nlm.nih.gov/m/pubmed/21773883/

That doesn't mean everyone with fibro and elevated CRP will have that snp, but it looks like there's another genetic fibro subset, anyways. Somewhat recently I posted with other studies pertaining to inflammation in fibro, something about a fibro study that found two genetic polymorphisms associated with 2 specific inflammatory cytokines.
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More inflammation info
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Post Edit, December 2017

Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. March 2017.
/www.ncbi.nlm.nih.gov/m/pubmed/28424559/

Also a Post Edit:
11/8/2015 Presentation @ meeting of American College Rheumatology & AHRP
Higher Levels of Pro-Inflammatory and Lower Levels of Anti-Inflammatory Cytokines Are Present in Fibromyalgia Patients
/www.healingwell.com/community/default.aspx?f=24&m=3548138

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A thread about inflammation studies is here. Over 30+ studies sought out by myself up to 2015, found some evidence.
/www.healingwell.com/community/default.aspx?f=24&m=2756942&g=2756942#m2756942

Post Edited (Rockon) : 12/29/2017 9:57:36 AM (GMT-7)

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