Relapsed HCV Viral Load with Cirrhosis

dhksaife

New Member

Joined : Sep 2009

Posts : 2

Posted 9/9/2009 4:50 AM (GMT 0)

Friends,

I was suffering HCV Gentype 3. My Age 42 yrs.

On July 2007 My Hepatologist given my Pegasys 180mcq + ribavirin 1200mg/per day 135mcq when platelet count decreases.

After six months of my therapy I found the report:

ULTRA SOUND: Portal fibrosis, Scarred Tissues & Mild splenomegaly
Had my pathology reports followed:

21.07.2009 ALT(SGPT):73 U/L
S.Bilirubin:1.0 mg/dl
Prothombine: 1.13 INR
HBsAg:Negative
Anti HCV:Reactive
HCV Quantitive: Less than detectable limits/Super Raligare SRL Mumbai
Andoscopy: Grade ii-iii Oesophaegal Varix
Moderate Degree of portal hypertensive gastropathy
Duodenal Ulcer
CBC & Blood Film: are normal except lower platelet count 108x10

After that they Made EVL
From the day the made EVL I was unable to eat very well,It was paining.
Doctor gave me some 3rd generation antibiotic
After that he made pathology test on

22/08/2009

ANA=Negative
SGOT=100 U/L
SGPT=125 U/L
Serum Total protein: 85gm/l (63-84gm/l)
Serum Albumin:38.00gm/l( - )
Anti –HBs:<3.0mIU/ml
Anti-HAV IgM:Non Reactive
Total Cholesterol:167.0mg/dl
H.D.L:51.0 mg/dl
LDL:102.0 mg/dl
Triglycerides:70.0 mg/dl
Chest P/A View:Normal
HCV RBA: POSITIVE
HCV RNA IN IU/ml:4.7x10(7)
HCV RNA COPIES :1.9X1(9)

It is wondering me! Is it possible to increase Virul load as mentioned with in a month?

My questions to you is it fatal for me to go on pegasys therapy while i am suffering Liver cirrhosis?

Thank you.

hep93

Elite Member

Joined : Jul 2005

Posts : 12014

Posted 9/9/2009 9:10 PM (GMT 0)

dhksaife, welcome to the forum. I am sorry you are struggling with liver disease. We are a support group, here for support and some information. However, we are not doctors and not able to give medical advice such as you are requesting, nor are we able to interpret your lab results in more than a rudimentary way. You need to meet with your hepatologist with any questions you have. I am sure that he would not subject you to something which would cause you greater harm or be fatal to you. I know that some years ago hep C treatment was not advisable for those with cirrhosis, but much has changed with information and treatments and they now do offer treatment to cirrhotic patients. This is something you need to discuss with your doctor and come to a decision based on your particular medical history and current status.

Good luck!

deedee48

Regular Member

Joined : Aug 2009

Posts : 148

Posted 9/10/2009 1:50 AM (GMT 0)

I have cirhosis ,very low platelet count,enlarged spleen,varicies,high pro time,I could go on and on,but my GI Dr.[also part of the transplant team] started me on very low doses of the same medicine,I tried it ,I hoped my body could tolerate it and it was risky. I had lab work every week and unfortunately after about 6 weeks or so I had to stop,due to my labs dropping danerously low. I could have stated bleeding spontaniously and at risk for infection. I was getting less than 1/2 the normal dose.

Good Luck My thoughts and prayers are with you,

DeeDee

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