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Posted 12/20/2011 7:13 PM (GMT 0)
Has everyone had this genetic test done.?

Mine was covered by medicare.

It is a Lab Corp test for genetic risk association
For inability to detox MOLD or LYME.

25% of population has this genetics and
Some inherit from both parents.

My test came back both parents have this gene.

MOLD symptoms are same as lyme and fibromyalgia
And untreatable depression. It also causes rage and insomnia
And anxiety.

Sinus infections are top on list along with asthma .

I have seen just recently friends health suddenly getting better
and i realized it was right after they moved.

The negative attitude was the first thing that
was suddenly gone along with this sense of no
longer being under attack by life.

And then the exhaustion was leaving.

I am posting about the MOLD thing again in hopes that everyone
will again evaluate their surroundings and back track to any time
They may have been exposed to mold.

I am hoping we can share remedies and situations.

Of course moving away from mold is key.

I got Shoemakers packet and bought his book.

I am looking for who else treats mold.
When i get $$$ i really want to persue mold issues
Before anymore of costly lyme treatment.

Meantime i am looking for least expensive for both.

Please ... Google around and investigate MOLD.

We have tragically lost one of our members and I
am seriously considering MOLD as possiblity for her
Never getting well and her loss of determination.

If you have a friend with fibro or
chronic fatigue please pass this
Along.

All the best in our progress and helping others
With our continued efforts of sharing love and information
this coming New Year.

Love,
Bucci
Posted 12/20/2011 8:32 PM (GMT 0)
Mold is a real issue. BUT, BEWARE of all the "mold inspectors" out there - many, many of them are just looking to scare you out of your money. Seriously. One possible way to guard against this is to get a mold tester who has absolutely no affiliation with a mold mitigating company....probably hard to find. But, these days, mold mitigation is big business and a lot of it is not above-board. Be a SMART consumer on this and do not fall for the shysters out there! Okay - off my soapbox.

Plus, Bucci, I do not think the genetic anomaly is an INABILITY to detox mold but rather a retarded or diminished ability to detox mold (and some have more of a problem detoxing it than others regardless of the gene) - if you had a complete inability to detox mold, you'd be dead in less than a week as mold exists everywhere.... And, just be careful about shifting all the blame to mold. From my research it seems that mold is an issue with Lyme sufferers but perhaps no more than opportunistic viruses (mine is EBV) and any other thing that takes advantage of an immuno-suppressed body caused by Lyme. Good topic, but I doubt it's a panacea cure for most with Lyme. As I have progressed towards getting better, I went down many rat holes convinced I had found the "answer" only to find it was either not an answer or only one piece of the big picture puzzle that I was putting together. Mold is indeed one of those pieces of the puzzle for many with Lyme.

Post Edited (yazzer) : 12/20/2011 1:35:39 PM (GMT-7)

Posted 12/21/2011 2:45 AM (GMT 0)
Right On, WWJD.
Posted 12/21/2011 4:26 AM (GMT 0)
My own 2 cents...Dr. Shoemaker's ideas have made a drastic impact on my treatment! I have one of the genes he talks about, so I'm not sure if what works for me will work as well for people without a detoxing deficit, although I have a hunch it would be helpful for anyone, and not incredibly expensive, so probably worth a try.

I have been taking cholestyramine powder 3x/day (pure cholestyramine - I believe the flavored kind is less potent) - and I've been seeing a lot of improvement, almost instantly. Before I started it I had hit a plateau in my treatment, but once I started, I began herxing more, which I think might mean that with the CSM clearing up a lot of toxin buildup, my body is healthier and more able to fight the infections with the abx I'm on, so it seems like more and more of this stuff is getting killed!

Unfortunately for most of us it's usually not just one thing causing us to be so ill (wouldn't it be easy if it was?). I will say that it is possible to get better while still living in a moldy environment. It makes it a bit more challenging, and perhaps slower, but if you can't get away from the mold, healing from Lyme is possible.
Posted 12/21/2011 2:29 PM (GMT 0)
Yup - the CSM helped me too and my LLMD prescribed it right away...I used to useit every day but, these days as I have been feeling better, I only do it maybe one time every week or two if the brain fog starts to get too bad again, or if I go up on a dosage of an abx or herbal. Agree with your assessment too, border. My point above about the mold is that mold can and is a real issue in some Lyme sufferers. But, there has been a whole shady industry built up out there that concentrates on "mold mitigation". You have to find a reputable company that does the testing and then one that will actually get rid of the mold or else you're just throwing your money away. Knowledge is power.
Posted 12/22/2011 4:56 AM (GMT 0)
hi there,

i got my HLA test results about 7 weeks ago and it revealed that although i don't have the lyme- or mold-specific genotype, i do carry the "dreaded" 4353 genotype which is the "multi-susceptibility" marker. (i also have the 1-5 marker which reduces hypothalamic function.) basically, my body cannot efficiently detox on its own so i am a sponge for any kind of toxins to which i have been exposed--metals, solvents, molds, lyme, etc. i have been on a methylation protocol and will start a chelation process soon as my metals are over the top high, along with my lyme & rickettsia infections.

my LLND said that he wants me to have an ERMI (Environmental Relative Moldiness Index) mold test done in my house where they analyze dust samples from the home to identify the presence of mold. they can identify the species of mold in this process as well from what i understand, and it is reported to be highly accurate.

just thought i'd ad my $.02.

blessings to one and all~
binx

Post Edited (binx67) : 12/21/2011 10:01:53 PM (GMT-7)

Posted 12/22/2011 3:49 PM (GMT 0)
wow, Binx!

thanks for responding.

I was just reading about those other configurations.

Have you tried VIP?

what are you taking?

what lyme treatment have you done?

Have you done heavy metal IV detox?

By any chance have you done ISAC panel for thick blood?

Heparin helps me most.

I see in the Surviving Mold book he talks about using the anemia
drug Procrit.

Have you been to Shoemaker.

Do you know any other doctors who are experts in what you are dealing with?

Thank you again for sharing your situation. I have feeling there are many others who are being bounced all over the place from doctor to doctor who have your genetics and don't know it.

Bucci
Posted 12/22/2011 10:16 PM (GMT 0)
hi bucci,

thanks for giving me the opportunity to put some of this info out there. i have felt a bit lost.

i just got my VIP results in and they are low, but i haven't reviewed them with my doc yet. i see him again in february, so maybe we would try VIP. i don't know. i haven't had the ISAB panel for thick blood, but will ask about that. i was suprised that my MSH was normal given my 1-5 genotype.

i have not seen shoemaker--i'm on the other side of the u.s.--but my doc and his colleagues are fully subscribed to his biotoxin dx methods and treatment protocols.

i am supposed to be starting IV chelation in the new year. currently, i am following the yasko methylation protocol: folate, vitamin B12, Phosphatidylserine, and a vitamin complex. i start edta suppositories (oh, joy!) this week.

after nearly 3 years of chasing an un-named illness, this is where it seems the answers lie. i still have MS fears, especially with my spectrum of symptoms, but with the HLA typing, metals urine challenge (very high lead, mercury & even gadolinium from all my contrast MRIs), lyme & rickettsia test results, maybe this is really it. i will be interested to know about whether mold is an additional contributor to my current state of ill health as well.

i am interested to hear what others have to say about their experiences with this, too.

blessings,
binx
Posted 12/23/2011 12:56 AM (GMT 0)
Binx,
Is your ACTH and cortisol out put off by
any chance?

What kind of work have you done.

What are your parents and siblings
Health conditions?

There is specific brain imaging test to
Get more specific about the hypocampi
Is functioning.

I am hoping too that others with these
Genetics can shed some light.

So much more has been exposed just this
Last year about all things in all areas that had
been in the dark or covered up even. I think
this coming year we will have more solutions.

I have gotten some relief from IV ozone but i feel it
doesnt last or i am still surrounded by toxins I can't handle.

I am working on finding a place to go out of my
current surrounding that is clear to see how i feel.
Posted 12/23/2011 1:23 AM (GMT 0)
Binx67, it's so great that you're finally finding the answers - isn't it great when all the pieces of the puzzles finally seem to fit together? It's a shame that it always seems to take so long for us to figure out how to get better, but it sounds like you're on the right path!

I saw Dr. Shoemaker years ago, but I didn't really have it all figured out. At the time I assumed I no longer had an active Lyme infection, so all I did was use cholestyramine and it didn't really work. But now I'm doing it all - treating my infections, correcting imbalances, and the cholestyramine and I'm finally making some progress with that.

I'm considering doing the methylation protocol after the holidays - please keep us updated on your progress! And good luck!
Posted 12/23/2011 2:59 AM (GMT 0)
Hey Border,
Im way off from having the pieces here but i do
see the end result of untreated lyme / mold
With my 2 sisters, my brother. My Dad who is on his
last legs from lyme and black mold in the house.

I am 100% sure all this led to my Mom death of
Leukemia after 20 yrs of unexplainable illness.


I cant live anywhere. Everything knocks me out.

Border, what is the natural type of anything that does what
The colestramine does.
I dont understand just what does it do that it gets to the mold??

Or is it not getting to mold but doing damage
Repair. Or is it emptying out clogged gallbladder??


Would bile salts supplement help??

How is Shoe getting mold out of brain??
Posted 12/24/2011 3:05 PM (GMT 0)
The mold creates, or is, toxins in the body - similar to the neurotoxins of Lyme. When you take the CSM, it binds to the toxins in the gut so that they cannot be reabsorbed into the bloodstream (which is supposedly the problem for those of us with this gene - we reabsorb instead of excreting toxins).

Only problem is as you excrete toxins, it frees up space for more to come out of your tissues, so it brings on A LOT of herxing!!!

Here's a list of natural toxin binders that I found - I have to admit I haven't tried any of them but it might help answer some of your questions.

http://www.herbsforlyme.com/category-s/184.htm

Good luck!

Posted 1/12/2012 7:19 PM (GMT 0)
I just did the Visual Acuity Test and it was Positive for biotoxins.

bucci turned me on to Shoemaker some months ago and I was interested, but foggy-brained it off my radar. Doh. bucci is some kinda researcher!

I have been following a neurosurgeon (jackkruse.com) and he just posted an article on Lyme, FM, that referenced Shoemaker. Kruse has an extraordinary ability to view things from above and tied in Lyme to his knowledge of Leptin and how it figures in.

But I'm back and just came from an NP's clinic where I dropped off a s-load of blood and saliva tests to see if they will work with me with the Shoemaker protocol. I'm not crazy about taking abx's, CSM, but I'm ready to swallow an atomic bomb to get me feeling better.
Posted 1/13/2012 1:51 AM (GMT 0)
Herbert,
this jack ruse site is the best thing I have read . I have changed my diet already and am already a new person.
I am feeling stronger and am walking around so much I kind of even have to teach myself how to walk right, I had
been walking around like I was a stroke person.
Now the ground is coming up to meet my feet.

everything Kruse is saying id right on and I see it so many other sick people around me.

thanks again.


love
Bucci
Posted 2/2/2012 1:27 AM (GMT 0)
Bucci,

I think Dr. Kruse is changing the medical paradigm. He said that the answers have been right under our noses all along. He's able to see the view from 30,000 feet and know what to do and look for using basic biochemistry. He has bio-hacked diabetes, obesity, heart disease, hormones, and most of the neolithic, modern diseases of inflammation.

I've been doing his Leptin Reset for 8 weeks now, and I'm seeing some changes, but there is something about leptin resistance and treating biotoxins that I need clarity on. Still digging.

His article on Lyme, Fibro, et al, changed my whole perspective on where I needed to go. I've immersed myself in Shoemaker and have begun testing. I'm thinking of getting the materials he offers for physicians to learn and show to a doc I found.

I'm so glad you're turning a corner and your words are the best I could ever read. Feeling better - what a concept! And you're experiencing it!!!

Your welcome, and thank you for bringing Dr. Shoemaker to my attention. Your enthusiasm for his work got me off my dead ass and now I'm moving forward again.

Herbert
Posted 1/17/2013 8:59 PM (GMT 0)
I have a son that has been through mold, lyme, bart, babesios, FL1953, morgellons, 6 viruses and fungus treatment at a clinic. If you want to see his improved blood, look at his pics on my blog
. Send me a PM for information on the clinic and doc where we have been going.

Post Edited (washem) : 1/1/2015 7:23:38 PM (GMT-7)

Posted 1/18/2013 6:31 PM (GMT 0)
Hey oldschool and bucci,

I just came across that Dr. Kruse this morning and was reading an article where I actually posted the link to it under "Something to think about." I have problems with cytokine release ( had a cytokine storm due to the lyme) , and I was thinking now that I read this thread that maybe it was due to this gene. I have been toxic a few times, body went into sepsis during lyme treatment. Maybe I am not excreting the toxins. Have you ever gone toxic during treatment?

I was also looking into the leptin thing. What syptoms have gotten better for you? Please keep me updated as I am really looking into this to help me recover.

Samantha
Posted 1/18/2013 6:48 PM (GMT 0)
Can someone tell me what exactly I will be asking for when I ask my doctor to take this test? Does the test just look for this specific genetic risk, or does it look for others as well? Any info would be greatly appreciated. I looked up some info, but it just doesn't seem to make sense to me...

Thanks,
Samantha
Posted 5/17/2016 2:02 AM (GMT 0)
Bumping this thread up in the hopes that someone out there can help me interpret my HLA DR genotyping test results, which I just got back today.

Turns out I do *not* fall into the mold-susceptible genotype (which is a huge relief), but, not surprisingly, I *am* susceptible to chronic Lyme. Specifically I have the 15-6-51 combination for chronic Lyme.


I'm familiar with Dr. Shoemaker's work and have some idea of what it would mean if I were suffering from mold-related biotoxin illness; but what does it mean to find out you're a Lyme-susceptible type?

For example, does it mean my immune system is likely to have a more difficult type keeping Borrelia in check on its own? That I am likely to be less responsive to antibiotics than other non-susceptible folks who have been exposed to Borrelia? Or does it have more to do with my body specifically having a difficult time getting rid of the neurotoxins that Borrelia produces? I know that I also have an MTHFR genetic defect that makes detoxing difficult, and I'm taking Deplin to help my body methylate better. But does being Lyme-susceptible mean, for instance, that I should be taking something really powerful like cholestyramine as a biotoxin binder? I've been reluctant to try cholestyramine because, paradoxically, my cholesterol is (and has always been) abnormally low; and this may be one reason -- apart from the havoc Lyme has likely wreaked on my HPA axis -- that my hormone levels are also super-low (cholesterol being one of the endocrine system's major building blocks). I didn't want to risk driving both my cholesterol and my hormone levels lower. But maybe I should be pulling out the stops with the binders, if not with cholestyramine then with something comparable?

Interestingly, my LLND was reluctant to have me get this genetic testing done, mainly because it's practically a foregone conclusion that the people who walk into his office are either Lyme-susceptible or mold-susceptible or both; and having this confirmed tends in his experience to make them unnecessarily fatalistic about their prospects for recovery. He also says that his approach to treating them is the same regardless, and he has seen plenty of folks even with the so-called "dreaded gene" get better.

My view was that knowledge is power; and I'm trying not to be fatalistic now that I've opened up this particular Pandora's box!

Just hoping someone can help me drill down a little more into what these results actually mean.
Posted 5/17/2016 2:06 PM (GMT 0)
Hi Delqueste,
Honestly, you might get more views of your post/questions if you copy this post and start a new thread with it.

I wish I had some answers for you, but I've never had those tests done. I can assume that I'm like one that has the genotype that is susceptible to Lyme, since I was infected at the age of 7. I also know, by experience that I likely have the MTHFR mutation due to the difficulties and types of difficulties that I have in detoxing. But those are only my assumptions, as I've not had the testing.
Posted 5/18/2016 4:50 PM (GMT 0)
I have been tested and found to have HLA B27 marker. Can someone tell me more about the HLA testing described here?
Posted 5/18/2016 6:24 PM (GMT 0)
I have the lyme hla 15-6-51. From what I understand it is that we have a hard time getting rid of lyme toxins. I was freaked at first. I take modified citrus pectin currently but may try cholestyramine to see if I notice anything. Strangely I don't herx much at all but really don't see much change with abx.
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