Well, according to Dr. Joseph Burrascano's "Advanced Topics in Lyme Disease" - which many LLMD's use as reference - for Lyme disease, he suggests that 400 to 600 mgs of Doxy a day be used - 200mgs two or three times a day. Although he is a supporter of IV abx with chronic Lyme.
There are many reasons why chronic Lyme treatments may not work. Viruses, co-infections -including other infections such as Mycoplasma and others, previous steroid use (for any reason), and others. Not to mention that a body has to be able to detox or it will be so overwhelmed with toxins that treatment must be stopped as the symptoms become too overwheling.
For an Ehrlichia infection, Dr. Burrascano suggest this:
"Standard treatment consists of Doxycycline, 200 mg daily for two to four weeks." So standard Lyme treatment can clear an Ehrlichia infection. Although, he also states that sometimes treatment with Doxy may not work, in which case he says: "consideration may be given for adding rifampin, 600 mg daily, to the regimen."
Of course there as many different treatment protocols as there are doctors treating these infections, so there are many thoughts on all of this. Be sure that whatever protocol you and your doc are following that you are seeing progress within months. If there is no progress, then something is preventing the healing. It's then time to start digging to find what is going on.
I would suggest that all read Dr. Burrascano's paper, "Advance Topics in Lyme Disease" as a primer for Lyme treatment. It can always be found in our "New to Lyme?" thread, but here is a link as well:
www.ilads.org/files/burrascano_0905.pdf