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Anyone feel worse after glutathione?

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Posted 8/14/2014 2:17 AM (GMT 0)
After my IV abx on monday and today I got dose of glutathione. Both times I felt horrible, shaky and out of it for a couple of hours. I was just wondering if anyone else has had a bad reaction to it? I was so hoping this was going to be the magic potion. Everything I read about it says it's a wonder drug. Any ideas on why I would react this way?
Posted 8/14/2014 3:02 PM (GMT 0)
Yep!
Not the orals, that I've noticed, but the IVs cause me to herx (at least I believe it's a herx), usually lasts a day or two and I feel extremely tired and usually very emotional. Then I usually feel much better by the 2nd or 3rd day. My integrative doctor told me that these could definitely cause a herx because its boosting the immune system and removing toxins.
Posted 8/14/2014 4:35 PM (GMT 0)
Yes. I feel bad for a few hours usually. Very tired and weak. Only the IV though. Orals don't seem to do that to me.
Posted 8/14/2014 6:10 PM (GMT 0)
Hi pictureofhealth,

I have heard of this and if you search on the internet quite a bit comes up in regards to herxing from glutathione. That may just mean that your body has a hard time detoxing, or your body is depleted in glutathione (making it harder to detox) and then when you get it, it is somewhat overwhelming. Not necessarily a bad thing - it is probably working then and getting toxins out.

I would just keep track of how you feel with it and hopefully - the more you continue with the IV's, the less intense the feelings might be. Drink lots and lots of water after you do an IV (I know you probably already are smilewinkgrin )

Do you just feel a bit off for a few hours?

~beth
Posted 8/14/2014 7:00 PM (GMT 0)
I feel tired and very emotional for the entire day, the day I have it done. But my doctor said its a herx
Posted 1/15/2015 6:21 PM (GMT 0)
I started IV Glutathione at an extremely low dose and got very sick for about three days with exhaustion, low mood, and generally feeling weak and ill. I researched it a bit and spoke with my doctor and it seems that for people who have, a) very low glutathione to begin with from chronic illness or a genetic inability to produce enough, and/or b) have a very toxic system will herx from Glutathione. Basically what I discovered is the more you react, the better the effect - it means your liver was backed up and your immune system was down. The glutathione is clearing things out and helping to rev up your own Immunity. We reduced the amount for the next visit and I was able to tolerate more gradually, and without any problem.

If you are on any medications, keep in mind that the glutathione may push them through the system faster, especially that day. I am on SSRI's and I noticed a change in my mood and a headache when I started so I took my pill after my glutathione so that it wouldn't get washed out so quickly.
Posted 1/15/2015 6:34 PM (GMT 0)
Yes! My doctor had me take liposomal glutathione (smells like rotten eggs!) by Researched Nutritionals. I tried it two different times (2 different years) and I could only handle one dose of it. Nothing has made me feel instantly very angry and irritable like that stuff. It was almost like a major personality change within 30 minutes of taking it. I have had it mixed in a Meyer's Cocktail IV by my doctor before and didn't have the same reaction but I did fill nauseous. I wonder if it has something to do with being sulfer based. I don't have any sulfer gene mutations that I know of. It is one supplement that I have avoided because of that reason. Who knows, it has been a few years, with a lot of detoxing and treatment so I may not react the same now?
Posted 1/16/2015 3:26 AM (GMT 0)
Test with 23&me. Certain gene mutations do not like metholation aids. You might have the COMET mutation, if I remember correctly.
Posted 1/18/2015 1:25 AM (GMT 0)
I thought glutathione helps you remove toxins....and a herx, is when the toxins are being released from the microbes when being killed off, faster than your body can deal with it.
I don't understand how this can be a herx? Do you?

Do any of you feel like your doctor is making stuff up?

I did do some research, cuz I did have back pain, shortness of breath,whoozyness, chills, and fatigue after getting some IV glutathione. (yet, my jerking came to a stop, for some time).

Anyway, I think your body also has to metabolize it, brake it down...I need to do more research before I get my next dose. 2 doctors did tell me that some people have a hard time with it....while the one who gave it to me, said he never heard of such a thing....Something is happening inside, and I want to understand it.
Before getting another dose, I really need to do more research. I'm going to try to take it with molybdenom next time...and see if that does anything. It might help with metabolism, but I'm not sure.

I wonder if your doctor knows its a herx, and how that is possible. Or, if they make stuff up. I'm really curious about this, cuz I have the same problem.
Posted 1/18/2015 3:12 AM (GMT 0)
I had a LLND appt. yesterday and she said to get the 23 and me test to find out what my methylation pathways are.
So thanks ela9050 it sounds like you are right!
Posted 8/11/2016 6:24 PM (GMT 0)
hi guys. I have the same issues w glutathione.....IV makes me feel dizzy, headache, woozy, and just generally crappy. oral has a weaker yet similar effect. I've tried it three times in all and not noticed any significant reduction in symptoms. awaiting 23 & me results. i wonder too if i have either a toxic system or just can't process sulphur well (though i eat eggs and other foods containing sulphur no problem)

anyone have updates to their symptoms? pictureofhealth....how do you tolerate glut these days? or did you stop taking it?
Posted 8/11/2016 6:50 PM (GMT 0)
Generally speaking, oral glutathione is not the best for a Lyme patient, as very little makes it past the stomach acid. Liposomal or IV are the best options. This doesn't mean you won't get any benefit from taking it orally, only that it will be limited.

Glutathione is the master antioxidant produced in the liver, so when it's taken, it will help move toxins and we have to be sure that the rest of our detoxing pathways are in good working order (by using many different 'manual' detoxing methods like dry skin brushing and others) in order to not experience an overload of toxins.
Posted 8/11/2016 7:42 PM (GMT 0)

KatieB said...
hi guys. I have the same issues w glutathione.....IV makes me feel dizzy, headache, woozy, and just generally crappy. oral has a weaker yet similar effect. I've tried it three times in all and not noticed any significant reduction in symptoms. awaiting 23 & me results. i wonder too if i have either a toxic system or just can't process sulphur well (though i eat eggs and other foods containing sulphur no problem)

anyone have updates to their symptoms? pictureofhealth....how do you tolerate glut these days? or did you stop taking it?

How quickly are they pushing the glutathione? If it's given too quickly, you can indeed have those symptoms. When I was getting it, it was veryyyyyyy slowwwwwww push.
Posted 8/11/2016 8:01 PM (GMT 0)
I'm gearing up for my first glutathione IV and it's gonna be looooowwwww dose and veerrryyyyy sloooowwwwww and easy.

-p
Posted 8/11/2016 8:06 PM (GMT 0)
Oh goody P. Let us know how it goes.
Posted 8/11/2016 11:14 PM (GMT 0)
Go piro ..may help with detox ..as long as you dont have sulferation block it should be cool.. i push 1000 mg in 3 min 2 x a week ..can make you lil amped it is a vasodilator too...doc said melitonin high dose was as good or better antioxidant
Posted 8/12/2016 2:22 AM (GMT 0)
what is a sulphuration block and how do you know if you have it? i've been hearing a lot about people who can't tolerate sulphur have big problems with glutathione. any advice helpful or how to test for this.
Posted 8/12/2016 5:19 AM (GMT 0)
Its a cbs genitic mutation. .like the mthfr detox thang ...so you get a 23 n me test and run it through a site like mthfr or genitic genie and it tell you your snps .how well geneitcally you can hang or in my case like a person with out arms- cant hang..i believe ther are some post if you cross genitic testing ..
Posted 4/9/2023 3:51 PM (GMT 0)
Anybody got over acute respiratory syndrome after gluthatione IV? My sister is in ICU right now, she got high doses of gluthatione last December and she had a reaction 3 weeks after, started with itch and rashes then bodyaches, swelling and then a week ago intubated due to ARDS. Her treatment is symptomatic but I was hoping anybody had experience and tried fixing the overdose glutha instead of fixing just the symptoms. Anybody? Tnx
Posted 4/9/2023 11:27 PM (GMT 0)
Angelvy,

I’m not sure I understand your post. Are you saying that she developed ARDS as a result of the IV glutathione?

I have heard of glutathione being used as treatment for respiratory distress and cytokine storms in serious COVID cases, but if you’re saying this is part of a reaction to the glutathione she already had, I don’t know about that.

I just prayed for her.
Posted 4/10/2023 6:07 AM (GMT 0)
Thank you for the prayers 🙏
Yes, at first mild swelling and itchy rashes on her back, it appears after a week of the IV glutha, she had some IV gluthatione before but this time, she had a lot, with the swelling comes bodyaches, joint pains then she developed breathing problems and now intubated. A doctor told me that she probably had sensitization reaction to it and it will be gone from her system in few weeks but the reaction didn’t go away, it continues to attack her lungs, and because of the steroids she had for the severe rashes and itch, her immune system is totally down. The doctors are trying IVIG right now but also considering chemo. I am hopeful and praying that she will fully recover from it, but I don’t know the extent of the damage to her lungs. I read on this thread about heavy metal poisoning particularly mercury and also metabolism block but the doctors where she is doesn’t even consider that it’s from glutha, but some idiopathic respiratory syndrome but I feel that something is attacking/poisoning her organs.
Posted 4/12/2023 12:51 AM (GMT 0)
Angelvy I would really consider looking into the glutathione possibly having been contaminated. If I recall correctly, glutathione is extracted from yeast. The (possible) contamination might be affecting her lungs.

Doing a quick search this came up: https://www.fda.gov/drugs/human-drug-compounding/fda-highlights-concerns-using-dietary-ingredient-glutathione-compound-sterile-injectables

Talks about endotoxins in L-glutathione IV's etc.
Posted 4/12/2023 12:53 AM (GMT 0)
"One of the patients experienced low blood pressure and difficulty breathing and was subsequently transferred to a hospital. "
Posted 4/12/2023 12:54 AM (GMT 0)
" According to the report, the patient received an infusion of 12mL (2,400mg) of L-glutathione on October 17, 2018, and experienced sudden chills, fever and shaking, and was subsequently admitted to the hospital for a possible bloodstream infection."
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