Lyme and eosinophilic esophagitis?

Does anyone have any thoughts about lyme/co-infection and eosinophilic esophagitis? My son is making antibodies to every imaginable food (confirmed by skin and blood test).

Just trying to figure out if there could reasonably be a link between the two.

TIA!!

I'm reading a book called 'The virus within'- its about reactivation of the human herpes virus 6-the virus that causes childhood illness=Rosiola. CDC reports that 99.9% of the American population has antibodies for this virus-not because we've ALL actually been ill with rosiola, but because We've all been Vaccinated'

Anyhoo, point is that HHV6 has what's been referred to as a "gene reshuffling" effect. It can, and has been proven scientifically, that the gene reshuffling results in autoimmune responses such as seen in allergies. The eosinophilic is an autoimmune response-I have it and I have/had reactivation of the HHV6.

Has your son been tested for the human herpes viral panel that includes HHV6, EBV, and the cygomegalovirus?

Get tested for the HHV6, and heavy metals!

I actually have two kids with EoE so I am very familiar with it, thanks. I'm just wondering about whether or not lyme it coinfection can cause tissue specific eosinophilia. (I'm betting it can...eosinophils are parasite fighters too) We have always had normal serum eos counts.

Yes, I do understand leaky gut and am intending to work on healig his gut once our food eliminations brings my lyme IFA-positive son's esophagus under control. I do think he definitely deals with leaky gut.

He actually did have roseola as a young child. His HHV6 titers have gone from 1:320 in 2014 to 1:160 recently with no treatment (aside from food eliminations). We have myco pneumoniae level at 3.7-something (can't remember off top of head). CMV is negative. EBV showed a cross reacting organism profile....I just don't know what....maybe lyme because his band 41 on igenex was +++ even though WB considered negative for both igenex and cdc (igm 18++, 23-25+, 41 IND, Igg=39 IND, 41 +++.

His mold IGE skin/serum panels are fine.

We haven't done heavy metal testing.

We have not done any treatment for recent lyme results. I am still waiting on coinfections to come back. Again....wondering if lyme/coinfections can hit the esophagus hard. ??

Thanks for all of your thoughts and comments!

As Razzle points out - even though the gov't says that's a negative test, it's actually showing that he has bands that are Lyme specific that are positive or IND - the only way to get any reaction on those tests is if you have the bacteria inside so that the immune system can make antibodies to it.

I JUST got back my results from an IgG food test....I make antibodies to just about all protein sources, beans, & a few oddball fruits....

My ND believes, and I also since researching the issue over 5 years now, that heavy metals toxicity is often THE ROOT CAUSE of this autoimmune response.

I had 8 weeks of I.V. chelation(synthetic amino acids that grab hold of metals), I retested and STILL revealed high mercury, lead, and aluminum. So I now chelate(detox) the metals using a product called HM chelate.

The heavy metals urine test is only $60, by Dr' s data

Your doctor is operating on outdated information in terms of what Lyme antibodies indicate, but is right that there could be a connection between Lyme and your eosinophilic esophagitis. Lyme is able to trigger all sorts of conditions that persist even after the active infection is dalt with, but unfortunately making antibodies to Lyme just means that your body has fought it - not that it has defeated it! Lyme can morph into dormant forms that stay in your body for life, waiting for an opportunity to reactivate when your system is weakened. Many people make antibodies for life, and there's no reliable way to know for sure whether the symptoms and conditions that appear even years later are from continuing damage Lyme caused in the past or from current reactivation of infection. This is why many people with any history of Lyme and most Lyme literate physicians (LLMDs) will recommend antimicrobial treatment when someone with a known tick-borne infection history develops symptoms.

Were you diagnosed with EE with a biopsy during an endoscopy? Do you have high eosinophils in blood tests as well?

Have you had food allergy blood testing performed? How are your symptoms and eosinophil numbers when you don't eat the list of foods you mentioned?

When I see a long list of food allergies and intolerances in someone with a TBD history, I think about mast cell activation syndrome (MCAS). MCAS is common with TBD (and in long COVID and some other conditions) and causes to body to react with allergy-like reactions, including anaphylaxis sometimes, to anything that contains high levels of histamine or triggers histamine release in your body. I found relief from severe food limitations and high eosinophils with a few weeks of oral cromolyn sodium taken before meals. (MCAS caused other symptoms for me as well, which I addressed with other mast cell stabilizers and a low-histamine diet.)

Have you seen a LLMD in the course of your treatment? How were you treated for Lyme in the past?