Borrelia DNA has now been found in Brain Tumour Biopsies

Scary! It almost seems like borellia is turning out to be the root of all evil!

mpost said...
Having a lot of respect for Dr Alan Macdonald's work, i'm growing a bit concerned about these research papers published on blogs all over the internet. Scientific papers need to be published on peer reviewed journals, otherwise nobody will take them serious.

It is indeed much harder to achieve that, but it's how science has been created: evidence needs to be so clear that nobody can deny, not even malevolent peer reviewers...

Yeah, I freakin love Dr Alan Macdonald, and I truly believe he is on to something and asking the right questions. But I agree with your comment, is he submitting these findings to peer reviewed journals? if he isn't, why isn't he would be my question.

I am Alan B.MacDonald,MD.

My discovery of Borrelia burgdorferi DNa in tumor cells from
5 patients with Glioblastoma multiformae is the first
of its kind in the world literature.

Some have wondered why I post my discoveries on
websites before attempting to go through the formal
process of publication in peer reviewed medical journals.

I establish the priority and the originality of my discovery
by use of internet postings.
I share the information with patients who have illnesses
which relate to the discoveries which I have made.

I do this to immediately share my knowledge with
others, who I hope will repeat my research and
arrive at identical conclusions.

In my past research, I have learned that
manuscripts which I have submitted take
months to be reviewed, but are eventually
published.

My list of peer reviewed publications is available
via Scholar Google [ search terms "MacDonald" and"Borrelia"

I do intend to complete additional steps in my research study
of Glioblastomas and Neuroborreliosis { Special Staining of tumor Tissue
beyond the DNA Probe studies which are contained in the
images which are now in the public domain.

I appreciate your support and words of encouragement.
It is the Glioblastoma multiformae patients
who NOW and Immediately
Need this Information.
Survival of Glioblastoma multiformae patients is measured in months
from the time of initial diagnosis.

Respectully,
Alan B.MacDonald, MD, Fellow ,College of American Pathlogists

Dr. MacDonald,
A very warm welcome to you! Thank you so very much for joining and posting in our community! We are very excited to have you here!!

You surely don't need me carrying on about how valuable and wonderful your work is, as it definitely speaks for itself. Thank you so much.

Dr MacDonald

Thank you very much for your participation to our forum. We really appreciate that you took time to inform us about your publications.

Thank you for your pioneering research and support to the Lyme community.

MarieLS

Here are extracts from a 2008 Scandinavian study which found links between Borrelia and Lymphoma ("MCL" in the text stands for Mantle Cell Lymphoma".)

I will post more examples from the literature soon.
Elena


"Discussion

In this large, population-based case-control study, history of Borrelia infection was associated with a nearly 3-fold increased risk of MCL, whether the exposure was self-reported or based on serologic evidence, even in patients with no recollection of Borrelia disease.

An association between Borrelia infection and lymphoma development has been suspected since even before the identification of the spirochete in 1982.21 Accordingly, the occurrence of lymphoma in close proximity to typical skin manifestations of borreliosis, such as ACA and lymphadenosis benigna cutis, has been described in several case reports.22,23

However, other and more tangible evidence of a causal association in certain lymphoma subtypes includes elevated titers of anti-Borrelia antibodies described in individual patients with primary cutaneous B-cell lymphomas (PCBCL),8,9 a higher anti-Borrelia antibody seroprevalence among PCBCL patients than among controls,10 cultivation of the spirochete from skin lesions of 2 PCBCL patients,13 and demonstration of Borrelia DNA in cutaneous B-cell11,12 and T-cell lymphoma lesions24 by polymerase chain reaction (PCR) techniques.

Until recently, there has been little evidence of a Borrelia-lymphoma association in studies outside Europe....

However, serologic evidence of previous Borrelia infection was found in chart reviews in 10 of 23 patients with PCBCL in a recent American investigation.28

In our investigation, there was little solid evidence of a predilection for the skin among the lymphomas that could be suspected to be causally linked with Borrelia infection. Rather, we found evidence to suggest an increased risk of MCLs among those with a Borrelia infection history. We recently demonstrated the presence of Borrelia DNA in 2 nodal lymphomas, 1 of which was an MCL, diagnosed in patients with a documented history of Borrelia infection.16 However, previous studies, albeit with a focus on PCBCL, have suggested associations with risk of MZL, FL, DLBCL, and T-cell lymphomas.12,24,28 Moreover, Borrelia DNA has also been detected in cutaneous B-CLL infiltrates,29 analogous to one of our seropositive patients.
.....

In conclusion, for the first time, we found evidence to suggest an association between Borrelia infection and risk of mantle cell lymphoma. This novel observation requires confirmation, for example, from studies testing for the presence of Borrelia DNA in tumor tissue or from investigations nested in cohorts with access to serologic, register, and/or interview information about Borrelia infection."

DOI: http://dx.doi.org/10.1182/blood-2007-08-109611

Thanks Elenacook.
Everyone should read the post you refer to.
I used to think that the use of antibiotics was the reason the government denied help to people with lyme until I saw years ago that it is common practice that people with lyme recover with herbals, if they know what they are doing. That leaves only one reason for the government position - the unspeakably corrupt bioweapon warfare.

Post Edited (trumpet123) : 1/24/2016 4:27:49 PM (GMT-7)

Thank you Elena!

Long ago it was postulated that Borreliosis can re-activate a latent EBV infection.

The issue with EBV, Hepatitis B, H. pylori AND borrelia causing cancers is bound up with the fact that they are CHRONIC infections.

Cancer does not generally happen overnight. Acute infections that are easily eradicated by the immune system or by short courses of antibiotics are not around in the body long enough to do the "accelerating" of dangerous mutations that is necessary to produce cancer.

**Chronic** infections have all the time in the world.

Elena

So new here all I can say is Thank you to the Dr on this research,I hope ears are listening to all this information coming out on a global scale.....if not now,soon.

Thanks Dr MacDonald for all you have done.

I appreciate that you have made the information available to us. I don't see it as any different than Dr Horowitz doing tv interviews to get the word out or Stephen Buhner writing books to help people get treatment when Drs have failed us or refused to help.

I personally think that the problem is more that our medical system is own in whole by Insurance companies and Pharmaceutical companies. Insurance companies don't want people diagnosed because treatment is expensive. Big Pharma makes lots of money on meds we take to treat symptoms.

Personally, the medical system has completely failed me. I started having headaches at 16 years old. Thirty-seven years ago. At least a hundred doctors, many medications, physical therapy, hypnosis, biofeedback, ...

In the last two weeks I have been dumped by two medical practices. The person who first suggested Lyme was my eye doctor. I was lucky it was the subject of a professional lecture - not by a Lyme doctor but by a doctor who is the husband of someone who went from doctor to doctor until someone decided to test her for Lyme.

The doctor that most recently dumped me (I only saw her the one time) said there was nothing she could do. I didn't mention Lyme. I only mentioned Fibromyalgia. She patted me on the head and said I just needed to do yoga and feel better about myself before referring me to another pain clinic that won't treat me either. When I asked about LDN, she interrogated me about where I heard about it. She said I shouldn't be reading things on the internet.

Some doctors get their noses out of joint when they think you know something about your disease. They want to be the authority on everything. I once had a doctor say to me "you will always know more about your disease than any doctor, but you can't tell them that." He was 100% right, but my best doctors have always been those who treated me as part of the team.

I was an engineer before I was unable to work. I am perfectly capable of reading an article in a scientific journal. I'm also capable of making decisions about my health. Whenever my doctor gave me another option, he would tell the good and bad. He usually had me research it to see if it was something I wanted to try. I made the decisions because ultimately it is our decision as patients.

So thank you Dr MacDonald for doing us the complement of making your findings available to us and thank you to everyone on the forum who shares their knowledge and experience. I finally have hope that after 35+ years I might actually get better.

Kim

Thank you for reviving this thread - it's happened just at the right time, as Dr MacDonald has made some further discoveries since this thread was started which are truly earth-shaking in their implications.

Dr MacDonald has found Borrelia endosymbionts INSIDE parasitic nematode worms in Glioblastoma multiforme tumour cells.

Endosymbionts are microbes that live in "co-operation" with their hosts, the nematode worms. Hiding inside the nematodes, the Borrelia bacteria are protected from the immune system and antibiotics.

So even if a patient were to successfully eradicate all free Borrelia, theoretically the Borrelia could continually replenish their numbers from the bacteria inside the worms.

Dr MacDonald tested tumour cells from 5 victims of Glioblastoma multiforme and found the borrelia - plus - nematode scenario in ALL FIVE.

Additionally he found the borrelia endosymbionts inside parasitic nematodes in ten out of ten samples of CSF from MS victims, as well as inside the "lewy bodies" (diseased areas of brain) in the autopsy brain tissue of a patient who died of Lewy Body dementia.

There is an excellent video here by Dr MacDonald where he presented his findings at the London conference of the AONM in mid-May this year.
https://vimeo.com/166688480