JDB15-
1) "Something" is causing a lot of ailing people a great deal points to infectious disease spread by little bitty creatures. Everyone here understands questioning & challenging. But when patients visit 20 doctors, they either succumb to their disease or begin their own investigations. Many along the way are fortunate to find a worthwhile doc to prescribe antimicrobial, etc & then their vast array of crazy, debilitating symptoms can improve.
2) Good to hear you are getting better, yet the very product you endorse does discuss the LD bands on its website. So as a doctor, perhaps you need to contact them. They apparently do have some incorrect information on their website, as Traveler mentions, re band 41, one that is cross-reacting.
3) You question a relatively fresh blood sample sent, saying the IGG makes no sense, but also what makes zero sense is governing powers dictating to medical centers, denying help to patients. "Something is rotten in Denmark" (tho, of course, not limited to DK).
To that very point, Willy Burgdorfer, whom the disease gets its name did say in an interview:
"The Lyme disease spirochete is far more virulent than syphilis. We don’t know the end yet. And [we] can’t even make a [blood] smear with Borrelia burgdorferi and see the organism. It’s there. But you don’t see it. You cannot find this spirochete. Why not? After all, I have a sick person here. He is trembling all over. His spinal fluid is full of spirochetes. But when it comes to blood, it’s not there. So there is something associated with this organism that makes it different."
Perhaps, as you are a doctor, you can access, US National Library of Medicine National Institutes of Health (NCBI) PMID: 17187579, Interview with Willy Burgdorfer, Ph.D. Interview by Vicki Glaser, entitled
"Vector Borne Zoonotic Dis. 2006 Winter;6(4):430-3" I ask you to do so, as this is somehow no longer available for the public to see?
Why is this striking 1987 title abstract no longer available?: "Stillbirth following maternal Lyme disease."
*Note-in the Lyme world, the authors of this, AB MacDonald & W Burgdorfer, are quite well known.
www.ncbi.nlm.nih.gov/pubmed/3480464Why is this 1988 article no longer available?: "Development of Borrelia burgdorferi in ixodid tick vectors."
Ann N Y Acad Sci.Burgdorfer W1, Hayes SF, Benach JL.
Can you access PMID #11245316? This is a 2001 from the J Clin Microbiol Infect Dis. 2001 Jan, entitled:
"Arthropod-borne spirochetoses: a historical perspective," by W Burgdorfer.
It is also one is also not available for me to see.
This 1993 one from Clin Dermatol is also no longer available?: "How the discovery of Borrelia burgdorferi came about
." Burgdorfer W1. Pubmed #8221514
I cannot view this one either:
"Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe."
Lane RS1, Piesman J, Burgdorfer W. Pubmed #2006870
This one seems to be only a partial, but interesting summary:
"Relationship of Borrelia burgdorferi to its arthropod vectors":
"IV International Conference on Lyme Borreliosis, a workshop was held to identify the unique development of the Lyme disease spirochete, Borrelia burgdorferi, in its established and suspected arthropod vectors. The following is a summary of the panel's discussions of research aspects concerning relationship(s) of this borrelia to its vectors, and the mode(s) of its transmission to animal hosts."
www.ncbi.nlm.nih.gov/pubmed/1947809This one in a 1989 Rheumy is available & I will cut & paste:
1989 Rheum Dis Clin North Am "Vector/host relationships of the Lyme disease spirochete, Borrelia burgdorferi."Burgdorfer W1.
Abstract
"Lyme borreliosis is now occurring on several continents where its causative agent, Borrelia burgdorferi, is maintained and transmitted by ticks of the "Ixodes ricinus complex" namely I. dammini, I. pacificus, and possibly I. scapularis in North America, I. ricinus In Europe, and I. persulcatus in Asia. Because all developmental stages of these ticks feed on a large variety of hosts including humans, the vector/host relationships of this spirochete is highly complex as indicated by the voluminous literature reviewed in this article. The association of B. burgdorferi with ticks parasitizing exclusively rabbits and birds, suggests that the geographic distribution of this agent may be far greater than assumed and may include areas where the disease in humans is absent. Finally, the persistence of the Lyme disease spirochete in the midgut of its tick vectors and its invasion of other tissues during the ticks' feeding, are unique and differ from the behavior of all other arthropod-borne borreliae."
This one from 1988 discussing N CA ticks (patients told for years that LD was really not a problem in CA):
"Spirochetes in mammals and ticks (Acari: Ixodidae) from a focus of Lyme borreliosis in California."
Lane RS1, Burgdorfer W.
"In northern California, antibodies to Borrelia burgdorferi were detected in 58 of 73 (79%), and spirochetemias in one of 26 (4%) black-tailed jackrabbits...The geographical overlap of different borreliae in ticks that bite wildlife such as deer may confound spirochetal serosurveys, and underscores the need for more specific serologic tests than those currently available." NIH PubMed #3280837
This one (PMID #9817862), from J Clin Microbiol. 1998, I am able to see & you might find interesting:
Tick-borne relapsing fever in British Columbia, Canada: first isolation of Borrelia hermsii.
Banerjee SN1, Banerjee M, Fernando K, Burgdorfer W, Schwan TG.
Author information
Abstract
"The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern British Columbia, Canada. The geographic area of exposure is a known focus of this disease dating back to 1930 when the first case was recognized in a human. Analyses of plasmid DNA, protein profiles, and reactivity with a species-specific monoclonal antibody identified the new isolates of spirochetes as B. hermsii, all of which were most similar to an isolate of this spirochete from northern California described previously. These are the first reported isolates of B. hermsii from Canada. " Pubmed #9817862
Here's a W Burgdorfer one here from 1988, entitled: "Tick-borne relapsing fever in British Columbia, Canada: first isolation of Borrelia hermsii."
www.ncbi.nlm.nih.gov/pubmed/9817862And this from 1997 also available re Rickettsia peacockii sp. nov., a new species infecting wood ticks, Dermacentor andersoni, in western Montana. NIH Pubmed #9103635
As many patients in the southern U.S. have also been told tick infections rare, this NIH article also authored by Willy Burgdorfer from 2005 is interesting:
"Tick infestations of the eastern cottontail rabbit (Sylvilagus floridanus) and small rodentia in northwest Alabama and implications for disease transmission." PubMed #16599149.
And yet another very interesting 1991 one from W Burgdorfer:
"Lyme borreliosis: TEN YEARS after discovery of the etiologic agent, Borrelia burgdorferi,"
"Since the recovery of its causative agent, Borrelia burgdorferi, in 1981, Lyme borreliosis has become the most prevalent tick-borne disease in the United States as well as in Europe. Its steadily increasing clinical spectrum now includes erythema migrans, acrodermatitis chronica atrophicans, lymphadenosis beniga cutis, arthritis, myocarditis, progressive meningoencephalitis, myositis, and various ocular and skin disorders. The true incidence of Lyme borreliosis in the world is unknown. In the United States, it has increased from 2,000 cases in 1987, to more than 8,000 in 1989. It occurs now in regions where the tick vectors, Ixodes dammini and Ixodes pacificus, are absent and where other species of ticks may be responsible for maintaining and distributing the spirochete. In Europe, Lyme borreliosis has been reported from 19 countries; its occurrence coincides with the distribution of the vector tick, Ixodes ricinus and possibly Ixodes hexagonus. Specific and dependable serological tests are still not available, but development of probes for specific antigens and the polymerase chain reaction appear promising in detecting ongoing infections and in identifying B. burgdorferi in ticks, animal, and human hosts."
www.ncbi.nlm.nih.gov/pubmed/1917043Post Edited (happyjo) : 7/15/2016 4:26:09 PM (GMT-6)