EBV (Epstein-Barr Virus, Mono) can cause both spleen and liver issues. There are lots of articles on this showing a connection between different liver issues (I don't want to scare you, so I won't mention them all), and liver mass is one of them.
It can also be the cause of spleen enlargement. I would encourage you to look further into EBV. Testing is fairly accurate for this and you can take Lysine to control the EBV virus. It's what I take to control mine, which can get out of control quickly if I'm not careful.
umm.edu/health/medical/altmed/supplement/lysine