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Amitriptyline helping Neuro issues? A request by a forum member other than me.

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Posted 8/14/2016 6:38 PM (GMT 0)
I was asked to post this for comments:

" I was misdiagnosed with Migraine Associated Vertigo and was put on Amitryptilene. Although it did not take care of my chronic motion sickness, it did help other neurological symptoms, and also helped with sleep. The neurologist gave it to me for headaches (even though i was not having any :) ). It is an older tricyclic antidepressant.

I want to see if Ami's helped anyone else out with neuro issues."

"How Do Serotonin Levels Become Deficient In People With Chronic Lyme?

A good portion of a person's serotonin supply is manufactured in the digestive tract while a person sleeps, and because many with chronic Lyme disease have a difficult time getting a good quality sleep, the stage for low serotonin levels is set. An interesting thought, however, is low serotonin levels could be the culprit for the poor sleep quality in the first place. So the cycle could start with the high stress of dealing with chronic Lyme disease reducing serotonin levels. This initial reduction in serotonin leads to insomnia or just plain poor sleep quality. Since the body manufactures a good portion of its serotonin supply in the digestive tract while it sleeps, a person with insomnia will not only have low serotonin levels, but it will be difficult for the body to replenish its serotonin supply because of the insomnia."

www.tiredoflyme.com/low-serotonin-levels-in-people-with-chronic-lyme-disease.html

From Trav: In looking at the link that was provided, I'm not really sure what the questions have to do with the article linked. This is a Facebook post that I was asked to post here, but it's from a closed group, so I can't link to the original post as it won't "go through" because you have to be a member of the group to see and post there.

The question from the poster though, about amitriptyline helping Neuro issues is what they wished to know.

Experiences anyone????
Posted 8/14/2016 7:32 PM (GMT 0)
I was looking into it ..i recently started supplimenting with mucuna bean extract it is a source of ldopa ..biotics has one ....also bee venom has some in it ...the ami is a inducer but wont make more
Posted 8/14/2016 11:06 PM (GMT 0)
Before lyme diagnosis - I was looking into a pain cream for my nerve pain...and I read about one that has amitriptyline in it - works on neuropathic pain. (It was combined with other pain meds - one been ketamine)
Posted 8/14/2016 11:41 PM (GMT 0)
Amitriptyline can turn you into a zombie. I was given a rx of 60 pills and still have 59 of them sitting in a jar slowly expiring. If you want to have the sleep schedule of a cat then I guess it works. Can't feel nerve pain when your knocked out.
Posted 8/14/2016 11:57 PM (GMT 0)
I think using a cream on an area of skin wouldn't be as 'strong' as taking a pill.
With the cream, you can also adjust the strength.
Posted 8/15/2016 12:05 PM (GMT 0)

bluelyme said...
I was looking into it ..i recently started supplimenting with mucuna bean extract it is a source of ldopa ..biotics has one ....also bee venom has some in it ...the ami is a inducer but wont make more

Hey Blue, I would be very careful with mucuna pruriens.... It can be addicting and also cause a worsening of dopamine-related problems since it can cause your dopamine receptors to become de-sensitized (meaning you will need an ever-increasing dose of mucuna pruriens to have the same effect) and cause a crash once it is discontinued. Following the logic, it could cause a Parkinson's-like condition once discontinued. It has also been known to cause schizophrenia in people predisposed to it.

If you are looking for serotonin, it does contain a small amount of serotonin, but almost none compared to the amount of l-dopa it contains, and the dopamine the l-dopa converts to is a serotonin antagonist (meaning it will lower your serotonin levels).

So, depending on what one is looking to boost, mucuna pruriens may or may not be a good supplement. AND, even if dopamine is desired, it can actually cause a desensitization of the receptors, unless it's being used very carefully and being pulsed.
Posted 8/17/2016 3:47 AM (GMT 0)
Thanks for the replies all. I was misdiagnosed with Migraine Associated Vertigo (MAV). Even though it was not correct, the Amitriptylene did help some of my neuro symptoms, especially the extreme head pressure that I would get. I was trying to see if others received help from ami's but I don't see enough of a response to get this info to our LLMD in Missouri.
Posted 8/17/2016 4:07 AM (GMT 0)
Personally for me, no.

It was prescribed for me to "cure" my Fibromyalgia which was really Lyme all along. Their reasoning was Fibro was caused by lack of REM restorative sleep and this(Elavil) would do the trick.
Years later when I got all my medical records from this office it was written down as for "depression". Which I'm aware was one of it's main uses at that time.

I took it for 5 years and I can't say it did much for me. I wasn't having headaches at that time, that I remember. During the 5th year I weaned off of it, it made me walk like a drunk when I woke up, plus I began having epileptic like seizures in my legs when I wasn't actually asleep. All that ended almost immediately after I'd finally taken my last dose. But having said that, this Dr. was also giving me quite a bit of random medications for disorders I didn't really have, so it could have been interactions.

The pharmacist suggested I probably had a buildup of it in my system and I should cut back.
Posted 8/17/2016 2:36 PM (GMT 0)
Thanks Julymorning for your feedback. You are correct, the main indication is depression. Even though I was diagnosed with MAV, I had some depression going on too and it was helped by ami's. As I get better I need to start tapering off of it. Isn't it the craziest thing that medicine you are afraid to go on, you also become afraid to go off of it even more :).
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