I made it through 4 years of hard study (Construction & Built Environment BTEC Diploma) fuelled on antidepressants (sertraline & fluoxetine). I didn't need much to get the desired effect. I would use fluoxetine for reading heavy material. It basically zoned me out to the point where I was able to sit and read for hours without the nervous/restless feeling I have normally, and which I think is lyme related.
I would use the sertraline for energy (practical side of study). I would never take both on the same day. Strangely I never needed to build them up in my system. I could take one pill having 5 days before then with nothing, for example, and still feel the full effects. I would joke with the GP that these work for me on an ad hoc basis but they never believed me. The conception is that you need to take them for weeks before you start to feel anything and you also need to stagger doses to eliminate withdrawal, etc etc. I never suffered withdrawal and I could leave as little as 1-2 days between changing the antidepressants. Sometimes I'd wait just 24 hours for the effects of one to clear out my system before taking the other. But then again my brain fog was so bad anyway, I probably would not have noticed side effects were there any.
I had to stop taken them towards the end of the course though because I did develop insomnia but only on the day I took the pill. The next day I could sleep normally. Normally for me would be bad anyway. This was all around 2008-2011 before I knew anything about
lyme. Got a tripple distinction on the BTEC