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Posted 4/9/2017 4:47 PM (GMT 0)

CD3764 said...
Before the invention of thyroid blood tests, doctors treated high cholesterol with thyroid hormone (low thyroid is a primary cause of elevated cholesterol). Lyme is famous for messing with our thyroids.

Have you had your thyroid thoroughly checked recently?

The TSH test isn't enough.

TSH is a pituitary hormone - everyone should have their actual thyroid hormone levels checked:

Free T4 T4 or thyroxine, free, direct
Free T3 tri-iodothyronine, free, serum

Healthy people have both the Free T4 and Free T3 levels in the upper half of the normal range...

Cd - That reminded me - that was something else my Dr said - she wanted my husband to get his thyroid meds and labs 'right' before we concerned ourselves with the cholesterol numbers. Thanks for reminding me.
Posted 4/9/2017 4:50 PM (GMT 0)

Psilociraptor said...
Hey traveler. Unfortunately this is just part of my global understanding of disease that i pieced together with my own research over several years. I don't off hand know of a concise papers on the topic. However, if you look for "endotoxin lipoprotein hypothesis" you're likely to find what you need. Or search for "LPS LDL" or "lipoteichoic acid LDL" or "lipopolysaccharide binding protein (LBP) LDL" and so on. It's been so long i can't really point you at the best paper. But in short lipoproteins carry LBP which binds endotoxins for excretion and both cholesterol synthesis and VLDL are transcriptionally regulated by inflammatory signals. There's an abundance of literature regarding that. The better question is where is the literature showing how cholesterol causes heart disease.

Very cool, Psilo!!! Thank you so much for sharing that much! It's a big help!! I don't really have the time I need to really research this for her, so you have given me a 'leg up' - thank you!!!!
Posted 4/11/2017 8:58 PM (GMT 0)
Wow this is a lot of info to take in.

Julymorning: Yes I'm on mino, zith, clynd and benicar. My dr is treating me for chronic inflammation.

I've been adding beans to my meals in place of meat. I'm working full time so when I get home I do not feel like working out. On my good days I try to walk my dog. If I could sleep 10-12 hours every night I would probably make it to the gym more often.

So what I'm gathering from the info I'm reading is that this is normal because of inflammation. What I'm worried about is if my cholesterol has been too high for too long, am I in danger of something happening?

Sorry, the answer is probably right in front of me but all the info posted is overwhelming. Can we agree that if I cut out the bad carbs and sugar and cut back on my meat intake that it should fix it?? Or because I have so much inflammation, this is something I'm just going to have to live with?
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