Rifampin and adrenals

We're new to the world of Bartonella and abx, but I've read in a few places that Rifampin can clear cortisol very quickly.

That was possibly the cause of an initial energy surge, which we no longer see.

Does anyone here have experience of what this does to the adrenals in the longer term?

I know Dr. M talks about Bart/Rifampin and adrenal issues. this is an excerpt from the Townsend Newsletter:

"Both adrenal health and thyroid health should be considered before treating with these antibiotics, especially rifampin, in order to allow the patient to better tolerate the treatment. Mozayeni has found that one pitfall in Bartonella treatment is related to adrenal fatigue. Adrenal issues must be identified and managed to optimize therapy tolerance. Rifampin, a cytochrome P450 inducer, causes a more rapid metabolism of sterol hormones and can lead to severe symptoms where a Herxheimer-like reaction is juxtaposed with a condition of depleted adrenals and low cortisol. This can put the patient into adrenal crisis with greatly amplified symptoms including severe pain and hemodynamic instability. This reaction may be mistaken for a Rifampin allergy and therapy stopped. Thus, withdrawal of a useful drug may result in a lost opportunity to treat and lead to treatment failure."


www.townsendletter.com/July2015/bartonellosis0715_3.html


Personally, I never had trouble with treating Bart with Rifampin as far as adrenals go...but I'm finding the Mepron is causing some fatigue (or it's a babs herx...not sure)

You might want to watch this Video - with Dr. Moyazeni (bart guru)


He talks about the P450 cytochrome and adrenal fatigue - especially with Rifampin treatment.
It's around the 1:17 mark

It's a really informative piece....so if you have the time....you might find it interesting.

ccc-better said...
Which video?

I think your link dropped off.

OOPS!

/www.youtube.com/watch?v=uYEHsRRxrQw

The second antibiotic is Biaxin.