DETOX not working? 180 posible liver detox mutations. D-Limonene helps in this area, fog, sleep,calm

This is important, and has never had its own post that I've seen in 2 + years. I've added this info to other posts in the past only.

CD's Detox post got me to post this not so simple, simple fact.

If your taking anything RX or suppliment that kill things (bacterial, virus, yeast or mold ALL and ANY), and feel like you herx real bad or just feel toxic, liver ALT AST tests are a must.

If you have been told you have Gilberts syndrome, (a liver flaw), also good to test liver enzymes.

Because you could have some of the 180 or more genetic liver mutations not mentioned on this forum.

23andMe (now more than $100?)genetic mutation testing can be an eye opener for your general health. The best program to decipher the raw data that I know is from MTHFR support, called the Sterling App (less than $50). Its 37 pages, a full page list 45 mutations. The Liver has 180 + here.

Liver mutations are some of reasons some alcoholics live and some die. It can also be a reason for non drinkers to still not feel very healthy.

A lot of what we think is herxing is your liver getting "clogged" from all this dead stuff. If you have liver genetic malfunctions, you will feel worse than other people here. This can effect gall bladder sludge too - and glucose issues are tied to this as well, even body pain and anxiety.

Very limited info on this, there should be more. Not many great supplements for this either.

I made a post titles "the wonders of D-Limonene" a short time ago. I took this sparingly for acid reflux years ago- and cured it. The Jarrow brand ($6 per month) specifically states its also used for liver phaze I,II detox, so I started to take it every night, the first week I slept like a rock, had more energy and felt more vibrant than I have in 25 years. Almost normal, but I forgot what that feels like. I might need to lower my thyroid med now - liver is where about 75% of T4 is converted to the cell consuming T3.

It can speed up or slow down other RX meds and 1000mg stays in you 48 hours, so its best to experiment slowly. I wish it came in 500mg for lower daily maintenance use.

I've taken other liver preparations, and felt nothing, zero. I'm sure some other supps out there help, but I have not found one yet.

Quit certain my 5 month herx on ABX was my liver gasping to live. Enzymes now normalized, but I still feel better on D-Limonine. This is weird, and I thought worthy of posting.

Post Edited (astroman) : 6/2/2017 11:08:28 AM (GMT-6)

YES a few more than 180. Might be a few more known, but MTHFR is the most complete.

180 more reasons (but related) that you might not feel well.

And Drs say Gilberts is nothing............you can be quite sure it does something to you, conventional medicine just does not care.

Gilberts and detoxing he// is why my Dr said to do MTHFR Support interpretation for 23andMe data. BINGO!

I agree Gilbert's is significant - if it can make the whites of your eyes yellowish...and cause fatigue...it's 'something'... I'm just perplexed to my seemingly permanent change.

I've been taking 1000mg D-Limonene daily since 2/15/16 and my latest thyroid labs show yet another drop in both my FT4 and FT3 levels.

I'm not blaming the D-Limonene...the thyroid level drops have been a monthly issue since I started Motherwort in October. I'm currently doing a N=1 experiment by ditching the Motherwort until my next thyroid labs.

This stuff makes me nutz lol

I'm just going to pretend I didn't see this one. There are already enough things. lol

"No, Antonio, your liver is fine. What mutations?"

I decided to invest in a 23andMe report. My sister's showed a MTHFR liver gene mutation. I tend to herx hard. Emailed this to myself so I would remember to add the supplement you suggest if it turns out I have the same mutation.

I certainly have made my greatest improvements since getting to the bottom of my mutation issues :) It was not a test I even thought really relevant, since I have absolutely no past medical history of anything since I was three I simply couldn't see how it would have any relevance....wrong, LOL!!

Since I got my detox sorted I have realised that, in hindsight (ain't that always 20/20) that I was basically on one year long herx, punctuated by having to come off my meds every so often. Now I can actually recognise a herx, like it has a beginning and and END, lol! No wonder I wasn't really getting anywhere significant, my body just wasn't getting the chance to sort itself out at all.

I know that all things mutational must have been doing just fine before Lyme, as I was never ill - like not ever. Which just goes to show how Lyme and Co can really screw up a system, hey.

Thanks for the extra info and links Astroman :)

Yes, I have to agree! I took SAMe before getting my results back - had a week of feeling better, then oh, so much worse, lol! I found through my results that I had to fix the rest before I could successfully add it to my protocol again. Now I do notice I feel worse if I don't take it.

It's a heeluva jigsaw, but now that I have my head round it (well, some of it, lol) I actually find it quite fascinating, and I guess I have Lyme to thank, or I would have never known any of it.

**I'm guessing any newbies here might have never read about D-Limonene, so here it is.**

I gradually tapered off the D-Limonene late winter. I wanted to feel any effects of my anti-inflammatory diet I started on new years.

Just added 1000mg of D-limonene back at bedtime a few nights (not in a row). It still makes a huge difference in sleep quality and I just feel all around much better the following day - helps thinking clarity, digestion, calmness, fatigue

**I'm guessing any newbies here might have never read about D-Limonene, so here it is.**

Some posts from last year on it:

"The wonders of D-Limonene; for GERD, Candida, liver and gall bladder detox, anziety, sleep + other":
www.healingwell.com/community/default.aspx?f=30&m=3586141

"D-Limonene WORKS!":
www.healingwell.com/community/default.aspx?f=30&m=3746453

Post Edited (astroman) : 6/2/2017 11:06:53 AM (GMT-6)

Welcome to our community, LymeKneeZ.

I’m not sure what you’re asking re: Gilbert’s syndrome.
Astroman will most likely be here tomorrow sometime to help answer some questions.

I haven’t checked my bilirubin lately - to see if it’s still low.
(I was diagnosed with GS many years ago and then after treating Lyme and co’S the bilirubin dropped and no longer considered to have GS)

Do you have Lyme disease?

Astroman,

Pardon my ignorance - I'm totally confused about this post. What I'm wanting to interpret from this info is there is an inexpensive supplement that helps some people with a certain mutation sleep better, have more energy, less anxiety and detox better due to a compromised liver. Am I totally off??

Thanks for a simple answer that my compromised brain can handle...
~Sarah

I've been taking D-Limonene for over a month and my liver enzymes are back up. I guess the coffee enemas were doing something because when I did them daily along with Liver GI Detox from PE they were back to normal.

On the plus side the enemas can be very relaxing. After holding in a bunch of liquid for 15min releasing it can be very relieving lol