Fenbendazole experience

Fenbendazole (fenben) dog wormer is being used to treat cancer, many are following this as a cancer treatment protocol.

Fenbendazole is an interesting drug, it is being explored by many for bartonella treatment, it seems to be effective and selective in the treatment of many pathogens.

I have seen reference to concurrent use in protocols with disulfiram mentioned several times. It has a good safety profile, is cheap and readily available as Panacur C or Safeguard.

The protocol I am following is detailed in the Joe Tippens cancer story rocks. Someone here mentioned Tippens several month ago, I dug into it, there are many testimonials about the effectiveness of this treatment in cancer. The mode of action in against the cancer cell sounds similar to the mode of action desired in a bacterial efflux pump inhibitor, I was hoping it might function as an efflux pump inhibitor.

My treatment with fenbendazole is now in the fifth weekly cycle. I am tolerating it pretty well, the first three weeks, 3 days on followed by 4 off, I herxed almost to the next dosage, not debilitating type herx. Cycle 5 (I am extending days on in this cycle today is day 4 on, I'll see how I feel tomorrow) herx much lower, much better tolerated. I believe fenbendazole has greatly benefitted my damaged vision. I document my visual field monthly, since last test December 29, to today January 28 major improvement. Three opthamologists said I would have no or little visual perception in my right eye, going from little vision to something better is really good. I am also breathing much easier, neuropathy has improved.

My existing peripheral neuropathy in my hands and feet initially increased on fenbendazole, and it induced profound discomfort inside both eyes which is new to me, high but tolerable level. In this fifth week the neuropathy is much less pronounced, the eye discomfort is almost gone, I am really thankful and blessed to have come upon this, at least for me.

Lapis,

Have you done any rounds of fen? What effect did it have?

Walking - I have done other anthelmintics, some of the Bryan Rosner protocol
Alinia - not much activity
Ivermectin - serious herx
DEC diethylcarbamazine ( I saw some improvement on this also, well tolerated)

I felt better initially with albendazole but subsequent dosing did nothing. I’d like to try fenben. I have one dose of ivermectin i can try but would that do anything?

I’ve also tried biltricide, alinia, pyrantel.

Cig

Give it a try, very low impact treatment.

My bart symptoms were largely neural/optic related. Initially floaters, than many floaters, optic neuritis, finally a Naion (optic edema) event. Neuropathy to hands and feet, brain fog, swollen lymph nodes.

The combo of minocycline/roxithromycin/fenbendazole was very effective for me.

Cignet
My neuropathy largely cleared up off minocycline. I was off minocycline for three weeks.
Unfortunately I had a major flare that largely concentrated in my eyes, brain fog, terrible shoulder pain.
I restarted minocycline about a week ago, symptoms have largely subsided and the visual has started to improve again.
I my have had a touch of covid.
I am still taking fenbendazole 3 on, 4 off, I tolerate it well, It's cheap and may have prophylactic benefits.

Post Edited (carlnpa) : 4/7/2020 6:41:05 AM (GMT-6)

Paulieinct - You mention a "cotton-wool spot." I have not heard this term, but I have central serous chorioretinopathy, which means that an area of swelling in my retina produces a grey blurry or blind spot in the central vision of my right eye. Is this what you have? I am curious because it's a rare condition that is associated with flares in cortisol, and only tenuously associated with Bartonella, so I'd love to connect with folks who might have insight and could swap research and what doctors have advised.

saraeli said...
Paulieinct - You mention a "cotton-wool spot." I have not heard this term, but I have central serous chorioretinopathy, which means that an area of swelling in my retina produces a grey blurry or blind spot in the central vision of my right eye. Is this what you have? I am curious because it's a rare condition that is associated with flares in cortisol, and only tenuously associated with Bartonella, so I'd love to connect with folks who might have insight and could swap research and what doctors have advised.

Saraeli: The retina specialist I consulted called it a cotton-wool spot, also used the term "infarct". He told me if it got worse, to go back to him. It has remained the same, altho it bothers me more and more. Like yours, it is a grey area in my field of vision, mine is a little below center. It is irregular in shape. The morning it happened, it first hit the left eye which resolved after a few hours. Then it hit the right eye and never resolved. My theory at the time was that it had something to do with Hizentra, which is the immunoglobulin product I was infusing twice a week. It is known to sometimes (rarely) cause clotting issues, particularly if you don't super-hydrate while infusing.

At this point I don't know what to do or who to consult.

Post Edited (paulieinct) : 4/21/2020 10:01:39 AM (GMT-6)

carlnpa said...
Paulie
That cotton wool spot is probably an area of optic neuropathy.
Look into NAION, non arteritic anterior optic neuropathy.
I have this, it progressed to complete vision loss in my right eye.

Fenbendazole (3/4) with minocycline, roxithromycin, various other abx anthelmintics definitely improved my vision.

This past round I used DMSO as a solvent for my 222mg active dose, on friday. Saturday morning I woke up in a really really bad herx. I took my third dose this am, all three doses in DMSO with yogurt. Almost two weeks of low dose rifampin now. I had been on DEC for four day last week also, discontinued after saturday herx.

See Joe Tippens "mycancerstoryrocks", the 222mg dose is for all weights.

I feel very good this morning.

carlnpa: What is DEC?

Yes, I did read Joe Tippens' blog. Very interesting.

You said you had total blindness in your right eye. How much vision has returned? Do you attribute this primarily to fenbendazole?

BTW, I recently completed a full-dose (500 mg) disulfiram course lasting 3 mos. and six days. I will probably post my experience in a separate post. Unfortunately, there was no improvement in my blind spot.

I did 60 days of fenben rotated 3 days on and 4 days off. Or vice versa. Can't remember for sure. But it helped me a lot. I no longer feel like the parasites are the biggest enemy. I think I will need to do it again though, because at the time I was not on anything for the parasite eggs such as clove. But I do think it helped based on the amount of herx symptoms I had.

Mr carlnpa, how strange things are. I was hearing about your adventure into Fenbendazole in a FB Bartonella forum but didn't realize it was you! If you remember we chatted ages ago about visual problems and Bart/Lyme. I am going to try the Tippens protocol. I am on Clarithromycin and Mino and Rifampin. So I just wanted to feed back info that might be useful to you. You mentioned floaters and then worsening floaters. Well I am trying out a 3 month protocol which is meant to have good improvement for floaters. It was a clinical trial of sorts. I came across it on YouTube an ophthalmologist (Doctor Eye Health) was going on about it. So I am giving it a try. It is very easy to do. It is just eating 1, 2 or 3 slices of fresh pineapple a day for 3 months. As you know pineapple contains Bromelaine. So the candidates who took the high dosage of 300mg (3 slices) saw a 75% improvement in their floaters. Those who took the medium dosage 200mg (2 slices) had a 66% improvement and the Low dosage 100mg saw a 55% improvement. Also try to discard as little of the core as possible because that is supposed to be the best bit, it usually gets thrown away because it's a bit woody. Good luck with everything.

carlnpa said...
Did the disulfiram do anything for your vision?

Unfortunately, no.

Fenbendazole 24 week update.

Pulsed 3 days on, 4 off.

Taking with 300mg rifampin 1 x daily trying to get to 2 x daily.

Roxithromycin 2 x 300 daily, this is the full lyme therapeutic dose, increased from single 300 to 300 bid on good blood tests 30 days ago.

Decreased minocycline from 100 bid to once daily, mino is causing me peripheral neuropathy, 100 is noticeable but tolerable and not increasing.

I added Montana Farmacy elderberry extract, I really like this, one of the few things I take that makes me feel better. Also added capsule elderberry extract Horbaach.

I take a bunch of other supplements including mixed tocopherol E, cod liver oil, 10,000i u D, 120mg lutein with zeaxanthin, NAC 1 gram, multi B etc.

My vision continues to improve with each round of fenbendazole, my retina specialist says he has never seen a recovery like mine. He says he has seen 100's with Naion, none of those with complete loss like I had made a come back.