Hooray! This Easter I feel like I am reborn and truly feel like I got my health back on track! 98%

Excellent! Thanks for sharing! My doc put me on minocycline and plaquenil ( and other things also ) as well. Glad to hear it works for you! Thanks for the info about the tinidazole.

Did you come to this protocol through a llmd or through your own research?

LymePickle, do you also have co-infections?  I, too, seem to do so much better on the tinidazole.  I am taking 250mg 3X daily and with no pulsing.

Patty

wonderful news lymepickle!!

I was feeling kind of down until I read your post. I am so happy for you. You did let me know a couple of things in your post...healing is not easy. Were there ever moments when you felt like you were going backwards but now you can see that it was all a part of healing?

Again I am so happy for you...I hope to join the 98% club or better yet the 100% and better club.

Much love!!!!

Thanks all for your kind words! I'm happy to share my wellness report and hope it shows we can all get well even though at times we tend to doubt it. These infections really take time to get rid of.

I am trying to figure out how mycoplasma fits into the picture with my original symptoms and I am finding the chills I had, occasional sweats, and inflammation, and pain in the chest could very well be from the mycoplasma. Now I know mycoplasma is ridiculously difficult to get rid of... I read someone said it takes 5 years of antibiotics! That is just too long, but I think that is on just 1 antibiotic. So I think a combo for this will definitely help. I found use macrolides, tetracyclines, or quinolone a to treat it. My plan is after a few more tini pulses I am going to change to azithromycin which seems to be well tolerated to help treat mycoplasma along with the mino.

Katebirch- tinidazole is particularly effective against anaerobic bacteria and parasites as well. I hate to say the mechanism of action, it destabilizes their DNA. Working right on the genetic level. So it's one of the more harsh antibiotics but it seems to be pretty selective at hitting these anaerobic bacteria. But keep this in mind as a potential risk when using the medication. I think I will need a longer pulse break than just 2 days next time around in case it has that effect on my own DNA so my cells can make the appropriate repairs. Also keep in mind Lyme DNA is very very long for bacteria and it runs right on the inside of their cell membranes.

http://www.dovepress.com/getfile.php?fileid=9965

There is some work on effectiveness of different antibiotics on treating Lyme disease. I wonder why minocycline was not researched? Does it have the cyst creating effect that doxy has or is it more like tigecycline. I believe the results of mino fall somewhere in between these 2.

Sure you can ask your doctor about tinidazole. Risks and benefits. It has got me amazing gains in my health in treating this Infection. A side effect is that it depletes vitamin B6 and vitamin B12 which could cause you fatigue so make sure to replenish your B-vitamins. Also a potential side effect is neuropathy in the hands and feet, kind of tingling feeling. But I didn't experience that. It is a very bitter taste even through the capsules. It is also better tolerated than flagyl which is very similar in molecular structure to tinidazole. Plus it breaks apart biofilms better than flagyl. Flagyl however may increase the risk of cancer and was tested on mice, tinidazole has not been tested for cancer risks but that is a possibility. The one important thing is do not consume alcohol while on tinidazole unless it is in small amounts like in your tinctures and should be consumed at different times that the tinidazole is consumed. Reason being is the alcohol reacts strongly with the tini. There is a downside to each abx... For example tetracyclines damage mitochondria, rocephin is hard on the gall bladder... My take on it is I want the bad guys out ASAP and I realize I have to do a repair treatment for the mess they left but at the same time I can clean up the mess. The sooner I can kick them out the sooner I can clean up the mess they made along with any damage abx may have caused

Tini in general just kills the Lyme pretty quick. It cuts their numbers down, what is left is mostly dead spirochetes and few of them. Also treats and kills cyst forms. It has excellent penetration into tissues as well. I was actually already asking for it on my first LLMD appointment to be honest be he gave me rifampin at first instead. He said rifampin and tinidazole can't be combined because the combo is too harsh on the liver. But I asked again on my follow up appointment because I wanted the most aggressive treatment I can get.

Is tinidazole absolutely essential to treat Lyme? No there are people that have stories of using herbal only treatments, and some people just took cipro and that knocked it out and they are healthy! The stories of success seem to vary so much.

The combo of it paired with a tetracycline like doxy or mino seems to be one of the most effective pairs reported.

Yes I read about it in Dr.H book. It is suggested that some of the best ways to prevent relapse from occurring is you have to add in a cyst busting drug like metronidazole (flagyl), or tinidazole eventually to a protocol. Grapefruit seed extract also works good and there are some people saying teasel will also work for this role. Plaquenil is considered a mild cyst buster but needs to be paired with an antibiotic and won't work by itself. This one particularly improved abx that are treating intracellular infections. So in terms of toxicity issues I would say Plaquenil and grapefruit seed extract are the least toxic and most tolerable of these.

Some Lyme doctors won't prescribe it in the beginning of treatment because the herx might be too intense. I heard of someone that died from a herx! I think it was going on IV abx, but still it could get that bad. Lyme doctors I think usually use it towards the end of treatment.

I have been treating it literally since 4 days after I caught this infection! I was infected on November 23rd. I was self treating though and I had a prior prescription for minocycline which I didn't use so I immediately got it filled and started taking mino. I ordered banderol and samento which was the next thing I used in treatment. For tini pulsing, I have been doing it for over a month since mid March and there were times when I felt like it would not clear like for example my prostate and knees which concerned me but there are noticeable gains each and every week. After my knees cleared I was like okay this really is working! Also the reason why it may have taken awhile in the knees is I may have just killed a bunch of them and there were just a big mess of dead bacteria there that needed to be cleaned out. Plaquenil I just started 2 weeks ago now.

Post Edited (LymePickle) : 4/21/2014 9:21:56 PM (GMT-6)

Great to hear about your progress Lymepickle. What do you mean by clearing infection in your prostate? Did you have prostatitis or what they now call Chronic Pelvic Pain Syndrome? I have burning upon urination on a daily basis and right testicle pain upon ejac. at times so was wondering what symptoms you had.

Okay thanks for the input. I may have to go back to abx at some point so it's good to know that Tinidazole was so helpful. Makes sense since Dr. Eva Sapi's research found it was the best drug to kill spirochetes, cysts and biofilm colonies. Doxy didn't even come close though some do get great benefit from it regardless.

http://www.ncbi.nlm.nih.gov/m/pubmed/21753890/

Ahh I think that is link will work. I tried the one I posted earlier and it said document could not be found even though I copied and pasted it directly.

If anyone is interested they can open that link and there is a file on that page that brings up Dr.S's work and shows all the data she got. Tinidazole apparently reduces by over 90% of both spirochetes and round body forms. In one part of the article it is mentioned that tinidazole can be as effective as reducing spirochetes by 94%, and 96% to round body forms. 1/3 of the left over germs are also dead.

Ya tinidazole is probably number 1 from her work. That and tigecycline but I am hearing that tigecycline wasn't that effective in clinical situations? Her reports even show tigecycline gets you to a plateau but them biofilms still persist and the subjects relapse "mice". She did actually in vivo testing on mice and the #1 treatment was the doxy + tinidazole combo. I wonder why she didn't do a test for minocycline?

Hi kate. Okay, to me your Dr. Has an okay protocol. I take it you have babesia as well? I think your Dr. has a huge push to treat your babesia first. That is what the cryptolepsis, artemisia, and Plaquenil can effectively treat. Keep in mind babesia is the infection that makes the other infections like 10 times worse especially when not yet treated. I am pretty sure I don't have babesia because I got this from a tear, also both my LLDs said I have no babesia symptoms, babesia is more a blood parasite than the other ones. What is norival?

Your cyst treatment is a very light one. It is the Plaquenil which is said to be a "mild" cyst treatment by some Lyme doctors in that it's use will prevent the occurrence of relapses. But I think what it really does is make the antibiotics like your minocycline work better inside of cells. You don't have effective biofilm treatment in this protocol, minocycline may perhaps be a slight biofilm treatment in that it has a slight chelation effect.

I called the office and left a message on their medical line asking about the cyst and biofilm aspects of my protocol. I am also going next week for one more blood test that is supposed to give good specific information.

Sadly...

I hate to report. There may have been an 'upper spine herx' where my upper back started getting really sore. Anyways I thought about the toxicity surrounding the use of tinidazole. And stopped using it yesterday, I figured I just wanted to give my body a break from it. I wanted to do some detoxing instead since I had quite a bit of upper back pain yesterday. The detoxing did help that.

Anyways, some symptoms came back after just 2 day break from the tinidazole. I went from being almost symptom free on Sunday. To feeling like things are fluttering around in my brain, knee flutters, odd muscle spasms, and a few tingles in my left eye which was all symptoms of this morning.

Right now it is my upper right back that really has me in pain.

I guess I gave a false sense of recovery with my thread! I said I'm 98% good! Well it is true I felt like that, but now I can feel the lyme came back in multiple areas in my body. It's kind of disappointing.

Also my 'exercise attempt' at taking antibiotics 30 minutes before exercise and then taking japanese knotweed and then exercising for 30 minutes. Well that knocked me out yesterday into bad fatigue.

I might try doing lighter exercise, maybe just for 10 minutes after taking the antibiotics, and then doing the stretching.

If noticeable Lyme symptoms come back just 2 days after stopping the tinidazole. It's pretty obvious I got a long way to go. I guess that's why they mean you have to treat for 2-3 months symptom free. If you stop treating at anytime you are like right back to square one again

I cut my treatment short and regret it now so stick with what's working. The black box warning is with Flagyl and even though Tinda is in the same class there may be less of a risk plus it was with mice. Even Prevacid or PPI's can cause tumors in mice and I've been on them forever and no cancer (well yet). I think it's worth the risk.