Thanks for the link to Dr Klinghardt's lecture. I've never listened to him before but starting at the 27 minute mark, he is 100% correct. I've always considered the bacteria as attempting to be symbiotic. He stated that he doesn't know how the bacteria reduce the zinc levels and I believe I do know. Our immune response is often referred to as the cytokine cascade and is initiated by substances called polyamines. These intracellular polyamines bind DNA, RNA, and almost all divalent cations like zinc and manganese. They are transported through the cell membrane and utilized extracellularly to help the immune system fight free radicals. This is where NO is produced. I have postulated that my protozoan acts similarly to Trypanosoma bruceii and increases ornithine decarboxylase concentrations. This initiates excessive polyamine production, especially spermidine. These polyamines bind more cations and cause more inflammation which leads to many of our problems. Our inability to replenish the lost cations in addition to the breakdown of our elimination pathways leads to issues of multiple systems. Since we all have a different microbiome, we have different problems. Since many have borrelia and we know quinolinic acid is a by product of it's metabolism, acidic synovial fluid occurs. I know nothing is as simple as it seems but using this hypothesis, I have been able to reduce my symptoms and suffering by replenishing what has been depleted. As we age, it has been proven that the intracellular concentration of polyamines decrease. Perhaps they get depleted as well due to my theory.
Post Edited (Georgia Hunter) : 1/19/2015 4:40:03 AM (GMT-7)