igenex results

Hi again, i fell like I'm bothering ppl with post, but i want to know if anyone can explain these igenex results for me....
IgM 23-25 +
31++++
39 ind
41++
58++
83-98 ++
IgG 28+
31+
29 ind
41++
58+
thanks so much in advance..... I haven't started any treatment... i'm trying to find out as much as possible before i get started to make sure i take the right path.

I have for a few years..... fatigue has been real bad the last 2 years. dizzyness (almost like vertigo) feeling like im going to faint, light sensitivity, seeing light flickers in my peripheral vision (scentilations are the technical term) extreme joint pain that migrates from joint to joint. been noticing changes in my vision recently. have had palpitations, PVCs , and funny feeling heart rhythms for last couple of years..... so far ive seen a neurologist (migraines without pain) a cardiologist, ortho, I worked for OB/GYN for last 6 years so ALOT of blood testing in his office.. and so many more.... so glad to finally have a something that ties it all together for me thought... i thought i was going crazy and so did everyone around me

i would assume i would be classified as late stage lyme since i have been symptomatic for years and have had no idea when i would have been initially exposed.... I know that as a child we all had a tick bite or two. was never a concern when we were little... my brother was also just recently diagnosed.. after comparing some symptoms i had him get his GP to test and it came back positive.

I actually do. that is who dx me, but soooo expensive... i have to get the money up to go back.... not sure how I will ever be able to afford it. from everything i've read its super expensive

thank you, I will check into some of these.

Thank you

Gkakmom
I think perhaps you have the IgM and IgG backwards - I believe the IgM is an active infection, and the IgG is an older infection.


It doesn't really matter anyway it it's IgM and IgG - I 've read that having positive bands in either means Lyme disease.

Gkamom - the ones marked B. burgdorferi like that are likely Lyme specific bands - I explain them below. If you are seeing something different, maybe you can be more specific with where to find this info, or you can copy and paste it into a post here, or you can quote the bands and I might be able to help.

Forgive me, I just copied and pasted the relevant information in here from a previous post of mine in another thread:

Here is the site that I use to help interpret the test results: www.reocities.com/HotSprings/Oasis/6455/western-blot.txt

An IgM result means that you have an active infection. It once was thought to mean an 'early' infection, but has since been revised. IgG means that the infection is at a later stage. The more +'s you have beside a number, the stronger the reaction.
IND means indeterminate - not negative, but not quite strong enough to be "fully positive". But it means that you reacted on those bands and should be considered, especially when they are Lyme specific bands.

A "Lyme specific band" means specific for Borrelia Burgdorferi, sensu stricto - Lyme disease in the strictest sense. There is only one on the over 300 known strains of Lyme that is considered Bb, ss. Nothing else will turn a Lyme specific band positive other than Lyme disease.

Bands 18 & 41 (whether in IgM or IgG) are indicative of the tail of the bacteria, which can cross react with other Spirochetal bacteria such as Relapsing Fever, Pintas and Yaws, and Syphilis.


Band 58 evidence of being in Poland from B. afzelii:
www.ncbi.nlm.nih.gov/pubmed/9972057

www.ncbi.nlm.nih.gov/pubmed/18328630

www.ncbi.nlm.nih.gov/pubmed/23540208

With a very interesting conversation going on about this here:
www.lymeneteurope.org/forum/viewtopic.php?f=5&t=3592&sid=4e5bf09031b0550b98e3e30c61a940eb

And - for those of you that like this stuff - I learned something new!! Band 38 indicates flagellin B!! A flagellin is the "tail" of the bacteria and there are two parts - A (like an outer coating) & B (like a core of the tail). Band 41 indicates flagellin A, so band 38 is detecting the outer sheath of the tail of the Lyme bacteria:
www.ncbi.nlm.nih.gov/pubmed/9573194

Melimom - A regular doc might not believe the results - he/she may say Igenex has false positives.
My Dr. (in Canada) accepted mine, though...I was surprised to say the least. My Canadian test was negative (the IFA was all they did)

You never know...worth a try...you may have him/her on your side throughout treatment...and that's a good thing.
It's been so good that when I see my regular Dr., she isn't questioning me on my treatment...and doubting that I have lyme disease.

Even if your PCP does accept the results, he still won't treat you for the length of time necessary...so you still need to see a LLMD or LLND.

melimom - Your LLMD will want to determine if you have co-infections or not...either by additional testing, but often just by your symptoms and how you respond to lyme medications.

Some Dr.'s will treat lyme first, others will treat a co-infection first, which usually includes a lyme antibiotic.

My first antibiotic was doxycycline...and 4 weeks later, zithromax was added. This was before I saw a LL Dr.

Doxycycline is a common first antibiotic, so is minocycline, Ceftin or Omnicef, sometimes Amoxicillin.

Some LLMD's will start you with two antibiotics right off the bat.

some Dr.'s do pulsing, others don't.

There are so many different ways to approach it. And each LLMD has his/her treatment plans.

IV abx are used for more difficult cases, or severe neurolyme. Or, sometimes, if orals don't seem to be working, a LLMD will want to do the IV.