Can I take Doxy at the same time as Rifabutin?

Hi guys so I'm currently taking Rifabutin every other day, Doxy every day and Zith three days a week.

I read that Rifabutin *can* lower serum levels of Doxy? What does that mean? Are the odds low, or likely? I know that Rifabutin is similar to Rifampin which interacts with many drugs like Doxy to reduce their serum levels, but Rifabutin is supposed to not activate those metabolic liver enzymes nearly as much as Rifampin does?

So should I be concerned that the Doxy I'm on will be significantly reduced while also on Rifabutin? Thanks!

LLMD's still do prescribe Doxy with Rifampin and Rifabutin...so I guess the benefits outweigh the chance of doxy concentration lowering.

LLMD MR says you can pair Rifampin with Mino, Azithromycin, doxy, biaxin. He goes on to state that it can lower both doxy and biaxin levels...but it's still in his protocol list.

Also - the Bartonella guru - Dr. M. - pairs Rifampin with biaxin...

Have you treated lyme already? I'm thinking if you don't have active lyme...then maybe it's not so much of a concern?

So, I wouldn't be too concerned. It's probably not 'significantly' reduced.

Re: Rifampin vs Rifabutin - I put Rifabutin in the drug interaction checker and it did say that. (not just rifampin)

Here's a link to the site in case you want to check yourself:

www.drugs.com/interactions-check.php?drug_list=2011-0,940-506

You could do doxy for a solid 4 weeks...and then add in the Rifabutin after. Knock down the Ehrlichia some.