Probiotic, antibiotic and supplement time schedule spacing question

Hi all!!

I was diagnosed about 2 months ago with Lyme and though other tests came out negative, my LLMD is treating symptoms for babs and bartonella. I have slowly started off with a schedule of minocycline 3x week, then after 2 weeks, I started azithromycin on alternating days 3x wk.
Then I started on nystatin 2x daily.
Now I just started mepron on Sunday with 1/4 teaspoon to slowly increase eventually to 1/2 teaspoon 2x daily.

Now, with the supplements plus probiotics which I take 2 a day (but with 2 different brands.)

My question is, I know it says "take probiotics a few hours away from antibiotics" is that only 2 hours away or can it be more like 5?

Is nystatin which is technically an anti fungal, safe to take anytime with the probiotics or is it treated like an antibiotic and has to be taken hours away from it?

Finally, can I take all the supplements with the probiotics? They are liver supporters and GI supporters.

With all these meds, it's hard to take them and not get some days messed up-because one antibiotic needs to be taken with food, the other on an empty stomach so I'm just trying to see how I can move them around. I've emailed my doctor but she hasn't gotten back to me yet.

And if anyone has any input, would you recommend pulsing the mepron? I feel like it's very strong and I always feel weird for a bit after I take it. And eventually I need to take t twice a day which means I have to deal with it in the mornings (I take all antibiotics at night) will my body get used to it and not react like that anymore?

Thank you in advance for any insight!
Karina

You want to take the probiotics when you're not going to be following it with antibiotics - they will just kill off the good bacteria in the probiotics.

So If you take your antibiotics say 8:00 a.m. and 6:00 p.m. (for example.)

You could take your probiotics anytime after 8:00 p.m. Then they have all night while you sleep to populate in your gut.

You could add an extra dosing at noon... after your lunch.