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Phosphatidyl Serine anyone?

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Posted 11/18/2016 4:03 PM (GMT 0)
Hi folks,

Since PNS symptoms have dominated my Lyme experience, I've always been interested in ways to help my nerves heal.

jrpsf shared this link awhile back:

/selfhacked.com/2016/10/25/myelin/#Myelin_Increases_Intelligence

While I'm already doing many of the things described in the link and my symptoms continue to s-l-o-w-l-y improve, I became curious about Phosphatidyl Serine and found this:

www.lifeextension.com/magazine/2002/9/report_ps/page-01

Has anyone taken the stuff and is willing to share experiences?

Thanks to all who post.
Posted 11/18/2016 4:14 PM (GMT 0)
I give it to my daughter to lover cortisol and to focus better, this stuff really works for brain.
Posted 11/18/2016 4:37 PM (GMT 0)
Thank you for posting this cd.

I looked at the first link - and was surprised to see that extensive list.

In particular - what stood out - pregnenalone and progesterone (two items in my 'arsenal') that I have been waiting to try.

..oh and CBD 1 cannabinoid receptor....

i remember about PS years ago - for reducing nighttime cortisol - there was a schedule to follow, but I can't even find the website anymore.
Prior to lyme, I was investigating some 'stuff' for my husband...and that's when I read about the PS - thought he had some adrenal issues. I can't remember how long he took it for...
I just asked him about it now...and he said it was effective for 'brain power'.

I didn't notice that with him when he took it..... tongue
Posted 11/18/2016 4:50 PM (GMT 0)
I had someone offer to share a bottle of phosphatidyld choline with me, but after some research, I discovered that it's made from soy - so I can't have it. But, what it did do, was get me to research further and I discovered that it's naturally in eggs. I have noticed lately that when I eat eggs for breakfast, I just do better during the day and sleep a bit better at night. I'm all for that kind of help!! So I now eat eggs as often as I can for breakfast and have been more stable at least.
Posted 11/18/2016 4:51 PM (GMT 0)
Thanks for the posts!

It sounds like PS is appropriate for those with adrenal issues. I'd feel better using it if I knew PS worked like an adaptogen (modulating) vs. reducing cortisol since I don't have issues with high cortisol at night. That's me and my situation, though.

LOL about hubby and brain power, Girlie. I was thrilled when jrpsf linked that list ;)
Posted 11/18/2016 5:18 PM (GMT 0)
Definitely is not modulating. I used it when my cortisol was high and it brought it down too low. What about lions mane?
Posted 11/18/2016 5:27 PM (GMT 0)

Traveler said...
I had someone offer to share a bottle of phosphatidyld choline with me, but after some research, I discovered that it's made from soy - so I can't have it.

There's a soy free that we use made with sunflower seeds.

https://www.amazon.com/Phosphatidylserine-Soy-Free-Softgels-Patented-Sharp-PS/dp/B00UP9T9JY/ref=sr_1_18_s_it?s=hpc&ie=UTF8&qid=1479489879&sr=1-18&keywords=phosphatidylserine&th=1

Traveler said...
But, what it did do, was get me to research further and I discovered that it's naturally in eggs. I have noticed lately that when I eat eggs for breakfast, I just do better during the day and sleep a bit better at night. I'm all for that kind of help!! So I now eat eggs as often as I can for breakfast and have been more stable at least.

Eggs are a good source but egg yolk has to be runny as heat will destroy the nutrients.
Posted 11/18/2016 5:30 PM (GMT 0)
This is also worth listening.

https://thequantifiedbody.net/repair-mitochondria-lipid-replacement-garth-nicolson-phd/
Posted 11/18/2016 5:52 PM (GMT 0)
Seems like Trav is talking about Phosphatidyl choline and I asked about Phosphatidyl sertine.

Googling Phosphatidylcholine resulted in this:

www.livestrong.com/article/33035-benefits-phosphatidylcholine/

I'm not sure about the differences, if any.


I took Lion's Mane for a very long while. The Buhner-recommended herbalist I consulted suggested I discontinue Lion's Mane and recently had me take higher doses more frequently of Dan Shen (Red Sage/Salvia Miltiorhizza). I'm finding this much more effective.
Posted 11/18/2016 10:22 PM (GMT 0)
Yes, they are both phospholipids, but I'm still a little confused about the two. Here are two articles that I have found, but am still trying to make a lot of sense out of:

lpi.oregonstate.edu/mic/other-nutrients/choline


www.sciencedirect.com/science/article/pii/0005276089902336
Posted 11/19/2016 2:02 AM (GMT 0)
I have body wide small fiber nerve damage. My LLMD team recently put me on phosphatidyl choline and serine to help repair the damage. One of the nurses who works on my case has a daughter who developed SFN from Lyme disease and has to wear a cooling vest when the temperature is above 75.

I'm not sure what type of nerve damage everyone has, but if you have small fiber nerve damage, then expect a longer recovery period since those nerves are mostly unmyelinated. On my neuropathy forum, it's emphasized that large fiber myelinated nerves can repair themselves in months, but small fiber unmyelinated nerves will take years to heal.

Also, Dr. Jay Coehn, who had erythromelalgia (a condition where people have a form of SFN), found that phosphatidyl choline was helpful to manage that condion.

www.medicationsense.com/articles/2012/emsup.php
Posted 11/19/2016 2:29 AM (GMT 0)
Is "phosphatidyl serine" the same thing as "phosphorylated serine" ?? I had a doc have me try the latter before LD diagnosis, I'm thinking it was to help my adrenals (says right on the bottle that it's an adaptogen etc.). He wanted me to take it with dinner and thought it would help me sleep better.

It did the opposite. Really made me hyper! And I did some web research (what could go wrong) and it seemed like some people it helps calm....but a few, like me, it makes hyper.

Aside - Does anyone else get overwhelmed with all the research and "research"? So many ideas out there, and a lot of them conflict with each other.... But I guess that's where we're at, and we have to be willing to take the time to learn, because no one else is going to do it for us!
BTW- that's not to knock the links that have been shared - thank you all for pointing them out...
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