Is it normal to feel nothing with rifampin?

On 600 mg for about 4 wks (300 mg 2x - first 5 days on 300 mg -1x) but only thing I notice is orange pee. Anyone else have no reaction - good or bad? I had high hopes for rif. Also on mino/plaq.

So only 3 weeks on full dose? I agree with Rikky - give it more time.

The other thing - try 600 mg once daily...that hit me harder than the 300 twice daily.

Yes, i am definitely staying on longer. Let's hope the answer is a low bacteria load!

I need to be on the rif to then add dapsone at some point. Surprisingly I haven't had my usual urinary issues or insomnia - which i thought were my versions of herxing. It has been 2 yrs and I still haven't figured out herxing.

If I'm being honest, my big worry is that I'm taking all these medicines and it may not be Lyme that is causing my symptoms. I'm sure I'm not the only one that feels this way - knowing that it is usually never "just lyme" and many people carry it and are asymptomatic.

We went on vaca for a week and I had a few symptoms disappear. I've thought about this endlessly - there was still stress on vacation so I don't feel that this is an "anxiety" thing. For some reason I get really defensive about that. I ate whatever I wanted and also had some alcohol. The symptoms that disappeared are the same ones that went away when we stayed in Ohio last summer - tinnitus, frequent urination and fatigue. These are easy symptoms to gauge. The tinnitus is still not back at a high level. We are moving this summer and I'm staying on the antibiotics until then - so that would be at least 4 months. If things get drastically better when we move then I know it must be environmental.

I'm on 600mg Rifampin dosed twice in the day, take this every other day. (I previously commented on my dosage in another thread and I had been wrong, I underestimated my dose, I am on a very strong dose).

I think I herxed a bit early on but not as much now. I def think bart/blo is my main driving infection. Do you usually herx with antibiotics (at least what you consider effective antibiotics for your case)? I didn't herx much with rifampin but the dapsone hit me hard with herxing. It will be very interesting to see how you respond to this medication.

I understand how hard it is to figure out what is causing what. It is frustrating to not have crystal clear answers and clarity on these issues. In a way that is nice that you are moving, will be interesting to see how your body responds to a new environment (hopefully the move won't be too stressful though). I know mold can be an issues for quite a few patients.

I almost feel that the more I reduce the pathogen load the trickier it is to dig deep and knock out the remaining load. I know it is still there as I still have some underlying symptoms (but much better), and I do herx when I find the right antimicrobial punch. Heck I herxed like crazy when I did the rife machine bartonella program. I didn't think I could still herx to such a degree, that blindsided me. Maybe it gets a bit trickier the further along we are, I feel like I've read this comment from a few patients, like the final 10% is the hardest to nail...

Is tinnitus not a common symptom for babesia? I have to imagine a lot of things can cause tinnitus though, these ridiculous infections are a jumbled mess, all tangled together criss-crossing symptom manifestations...