May have found a way to disable and treat Lyme neurotoxin

dacarte3 said...
I don't know if I'm allowed to post links to other commercial sites but google Alpha Brain. I've only heard good things about from Joe Rogan's podcast.

It has Huperzine in it:

"An extract from the plant commonly known as northern firmoss (Huperzia serrata), Huperzine A is a naturally derived acetylcholinesterase inhibitor. Acetylcholinesterase (AchE) is responsible for the breakdown of Acetylcholine, and so by inhibiting AchE, more acetylcholine is made available to the brain."

it even has cats claw in it haha, who knew.

240mg of Huperzine daily serving. I wonder if that is enough.

problem is that if you have a bad reaction to it, you wont know if it was the huperzone or something else.

source naturals has an inexpensive huperzine product on amazon. also, look at my post above about taking EGCG w/ the HPZ

dacarte3 said...

Lapis_29 said...

dacarte3 said...
I don't know if I'm allowed to post links to other commercial sites but google Alpha Brain. I've only heard good things about from Joe Rogan's podcast.

It has Huperzine in it:

"An extract from the plant commonly known as northern firmoss (Huperzia serrata), Huperzine A is a naturally derived acetylcholinesterase inhibitor. Acetylcholinesterase (AchE) is responsible for the breakdown of Acetylcholine, and so by inhibiting AchE, more acetylcholine is made available to the brain."

it even has cats claw in it haha, who knew.

240mg of Huperzine daily serving. I wonder if that is enough.

problem is that if you have a bad reaction to it, you wont know if it was the huperzone or something else.

source naturals has an inexpensive huperzine product on amazon. also, look at my post above about taking EGCG w/ the HPZ

I thought about that, just get huperzine standalone. But Alpha brain has many other goodies the body needs. And then throw in cats claw in there and that's one less herb I have to buy separately.

BUT, let's take this thing slow and take them separately.

So I need to google/research the highest quality HPZ+EGCG+Choline. I already learned Alpha GPC type of Choline is the best way to go.

This is my last hope. Wish me luck.

not to overwhelm you w/ info, but uridine seems to have a multimplying affect on choline when taken together. also helps to repair neurons

http://www.smart-publications.com/articles/choline-uridine-builds-new-neurons-and-protect-against-Alzheimers

--------------------------


http://www.sciencedirect.com/science/article/pii/S1074742703000248

''Combined uridine and choline administration improves cognitive deficits in spontaneously hypertensive rats''

https://www.ncbi.nlm.nih.gov/pubmed/18631994

''These actions are markedly enhanced in animals that have also received the other two circulating precursors for phosphatidylcholine, uridine (which gives rise to brain uridine diphosphate and cytidine triphosphate) and choline (which gives rise to phosphocholine).''

http://www.fasebj.org/content/22/11/3938.abstract

Animals received supplemental uridine (as its monophosphate, UMP; 0.5%) and choline (0.1%) via the diet, and docosahexaenoic acid (DHA; 300 mg/kg/day) .... As shown previously, giving all three compounds caused highly significant (P<0.001) increases in total brain phospholipids

So ELI5 in many studies it is shown they synergize very well. Particularly pay attention to last study, giving the trio of UMP/Choline/DHA has far greatest results then just supplementing DHA/Choline or UMP/DHA.

-----------------------------------------

also, I think CDP choline is best. Jarrow Formulas CDP Choline has reave reviews on amazon.

Post Edited (Lapis_29) : 10/18/2017 7:48:08 AM (GMT-6)

ok, sounds good

Lapis_29 said...

bluelyme said...
As part of our apitherapy tx i have ingested over a few kilos of royal jelly . This substance is very high in acetylcholine and other peptides .octopus grow back limbs with acetylcholine and im am noticing some of the wasting area coming back , Also as part of the pk protocol i have injected phosphtadylcholine and found sunflower lecithan to be a good nutritive source
/www.naturalnews.com/029069_royal_jelly_cognitive_function.html#

intersting

how are you able to get that much royal jelly? are you buying it in bulk?

One spoonful at a time - yes it is probably chinese but they take it pretty seriously. ...glory bee has it

Lapis,

you got me hooked on researching choline:

" The most important "muscle" for producing eye-popping mass is not really a muscle at all; instead, it's the major tenet of your central nervous system (CNS) muscle building processes, the neuromuscular junction (NMJ).

The neuromuscular junction is where the nerve cell ends and the muscle cell begins. This is the "transfer functional unit" where chemical messages from the brain (neurotransmitters) are delivered to your muscles.

Unlike muscles and organ systems, which are readily identifiable and easily quantified (for example, the right or left bicep), there are literally billions of neuromuscular junctions throughout your body, in your heart, eyelids and slammed all through your skeletal muscle (the type of muscles that you "flex").

So, big deal, you say? Yes, indeed, without neural input from the brain and spinal cord - in the form of neurotransmitters - the muscles cannot and will not act. Each muscle cell (or bundle of muscle cells) must be stimulated by CNS chemical messengers before they will move limbs and grow themselves.

If you can increase the efficiency or rate of neurotransmitter exchange across the neuromuscular junction, you can increase the power of each muscular contraction and the amount of work (reps x weight) performed during each set. More work means bigger, stronger muscles. Best of all, you can increase NMJ function without over-training.

The NMJ is where the tip of a nerve and muscle fibers meet, where, when called upon by the brain, electrical signals and chemical messengers are delivered deep within the muscle tissues. These neural transmissions stimulate a cascade of events including the release of calcium ions, the shifting of thick and thin filaments and mitochondria activation within the muscle. These deliberate intracellular events yield forceful muscle contraction.

With electromyography (EMG), scientists have determined that the stronger the brain's signal, the greater the electrical activity in the muscle fibers. So, while muscular growth is often attributed to the increase in size and number of muscle fibers, the fact that pumping iron, resistance training amplified neural response at the neural muscular junction may be more significant. Without the CNS, there is no contraction!

Neural stimulation of muscle fibers is not an all or nothing event. When the body needs to lift/move something very heavy or very quickly, there is extensive activity at the NMJ. With lighter loads, gentler contractions can be achieved through weaker neural signals to the muscle(s). The more muscle fibers you can neurally trigger for a longer period of time or at more frequent intervals, the bigger, stronger, and faster you become.

choline is an important component in acetylcholine - the principal catecholamine at the NMJ. Your muscles will not contract without acetylcholine."

So for the lymies that's experiencing nero-muscular issues this may very well be the issue. Lack of Choline means lack of nerve to brain, brain to nerve communication which means muscular issues. Issues from wasting, to weakness, to muscles not properly functioning (motor function).

I really do believe this is missing link I (we) have been looking for. Because nothing else is working.

Yes I did some research on uridine.

But what scares me about uridine is the connection to cancer and heart disease.

Yes, it's always pointed out it's the pharmaceutical uridine and not the natural supplement uridine but that's still too closely related to me.

Don't feel comfortable with that.

Also EGCG is well known to aid weight loss, something I definitely don't need right now.

I'm going to roll with HPZ + Alpha GPC Choline. One stops the proliferation of ACE and is neuroprotective and other one provides more ACE to the body.

That seems sufficient to me.

Post Edited (dacarte3) : 10/18/2017 4:03:45 PM (GMT-6)

Lapis_29 said...

dacarte3 said...
Yes I did some research on uridine.

But what scares me about uridine is the connection to cancer and heart disease.

Yes, it's always pointed out it's the pharmaceutical uridine and not the natural supplement uridine but that's still too closely related to me.

Don't feel comfortable with that.

Also EGCG is well known to aid weight loss, something I definitely don't need right now.

I'm going to roll with HPZ + Alpha GPC Choline. One stops the proliferation of ACE and is neuroprotective and other one provides more ACE to the body.

That seems sufficient to me.

honestly though HPZ alone isn't enough, its too weak in my opinion. You need the EGCG to really get the affect of promoting acetylcholine

I mean you are dying, why are you worried about weight loss?

Being able to fatten up is probably why I'm not dying faster.

Let me read again why EGCG allegedly makes HPZ work better and I may reconsider.

Standard Process is an amazing, affordable line of products. They try to keep things in their most natural state. I take their Choline. $13 for 90 tablets.

I also take Phosphatidyl Choline and Acetyl L Carnitine on alternate days. No side effects so far.

Pure Encapsulation EGCG is excellent also. I definitely have less neuro symptoms when I am taking these regularly.

I have to call my self out. Buhner does recommened Huperzine A. And he mentions beef liver multiple times for it is high in choline.

So he does address this some. I stand corrected.

Lapis_29 said...

cr3ativegirl said...
Standard Process is an amazing, affordable line of products. They try to keep things in their most natural state. I take their Choline. $13 for 90 tablets.

I also take Phosphatidyl Choline and Acetyl L Carnitine on alternate days. No side effects so far.

Pure Encapsulation EGCG is excellent also. I definitely have less neuro symptoms when I am taking these regularly.

try adding Huperzine a to the mix, see how that does. would be interested in the results

Yes, be a guinea pig with us.

Let's keep this thread alive and report back findings, progress (or lack thereof), possible side effects, etc.

We really need to test this out and test it out for an adequate amount of time. They normally say 3 months is a good mark to see if something is really working/helping.

huperzine a and alpha gpc choline comes in tomorrow. I'll also grab some EGCG.

But now the question, dosage.

Choline I'm reading 600mg a day. Huperzine I'm seeing a very small microgram dosage. I've tried to figure out way so small and only found one source talking about how potent it is in 100% pure form that, that's all that's needed.

Lapis,

what have you found on HPZA dosage?

Somebody said...
Royal jelly`s structure and composition is so unique that it cannot be replicated by man in any lab. The only lab capable of producing such an extraordinary substance is the bee hive. This superfood is rich in protein, loaded with B vitamins, and contains many other minerals and nutrients. One of the key ingredients in royal jelly that may have profound implications for improving memory and invigorating mental acuity is acetylcholine.

Acetylcholine was the first neurotransmitter ever discovered. It is found in the brain, spinal cord, and throughout areas of the nervous system. It regulates memory and is needed to transmit nerve messages from cell to cell.

Interestingly, royal jelly is the only natural source of pure acetylcholine.

Optimal levels of acetylcholine in the brain are associated with improved memory, fluidity of thought, and enhanced cognitive function.

dacarte3 said...
^^^wait should we do what blue lyme is doing and just eat royal jelly? Per blue lyme's last comments improvements are being made.

I am going to do the HPZ + EGCG + Choline + uridine + DHA and see what happens

already having good results with just choline + uridine _ DHA

will be ordering the royal jelly too and add that in later.