New Tuberculosis Drug Bedaquiline for Lyme Disease?

said...
Unlike many antibiotics, bedaquiline doesn't attack the bacteria directly and instead targets the enzymes that the disease relies on for its energy.

https://www.dailymail.co.uk/health/article-6307519/tuberculosis-cured-90-cases-new-drug-hailed-doctors-game-changer.html

Very interesting, wondering when this new Tuberculosis Drug Bedaquiline will be available to LLMDs like Dr. H and Dr.? It's recently helped "cure 90% cases of Tuberculosis."

It was already suggested by a Study back in 2014, Ying Zhang, it would be a good candidate for non-growing peristers of borrelia.

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4126181/

said...
Antibiotics that have good activity against growing bacteria (a low MIC) may not have good activity against non-replicating persisters, and vice versa.30 However, some antibiotics, such as the new tuberculosis drug candidates TMC207 and PA-824, have good activity for growing bacteria and non-growing persisters.3

TMC207 = bedaquiline

Some serious side effects with this one...
Saw Black box warning on one site.
(Long qt)
Half life 4-5 months

Hard on the liver.

“Very interesting, wondering when this new Tuberculosis Drug Bedaquiline will be available to LLMDs like Dr. H and Dr.? It's recently helped "cure 90% cases of Tuberculosis." “

Is it not available to them?
Or do they not see benefits vs risks?

I saw an ad for this new Tetracycline class antibiotic the other day: Omadacycline

FDA committee recommends omadacycline for approval - Healio
https://www.healio.com/.../antimicrobials/news/.../fda-committee-recommends-omadacyc...
Aug 9, 2018 - “Omadacycline is a modernized tetracycline antibiotic with the potential to help address the urgent and growing need for new agents to treat serious ... chief development officer for Paratek, told Infectious Disease News.

Looks interesting too.

Any guinea pigs